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Improving drug safety with a systems pharmacology approach.
Schotland P, Bojunga N, Zien A, Trame MN, Lesko LJ. Schotland P, et al. Among authors: trame mn. Eur J Pharm Sci. 2016 Oct 30;94:84-92. doi: 10.1016/j.ejps.2016.06.009. Epub 2016 Jun 7. Eur J Pharm Sci. 2016. PMID: 27287422
A Semi-Mechanistic Population Pharmacokinetic Model of Nusinersen: An Antisense Oligonucleotide for the Treatment of Spinal Muscular Atrophy.
Biliouris K, Gaitonde P, Yin W, Norris DA, Wang Y, Henry S, Fey R, Nestorov I, Schmidt S, Rogge M, Lesko LJ, Trame MN. Biliouris K, et al. Among authors: trame mn. CPT Pharmacometrics Syst Pharmacol. 2018 Sep;7(9):581-592. doi: 10.1002/psp4.12323. Epub 2018 Aug 16. CPT Pharmacometrics Syst Pharmacol. 2018. PMID: 30043511 Free PMC article.
Is Bioequivalence Established Based on the Reference-Scaled Average Bioequivalence Approach Relevant to Chronic Administration of Phenytoin? Perspectives Based on Population Pharmacokinetic Modeling and Simulations.
Kim H, Fang L, Yu J, Meng Z, Trame MN, Schmidt S, Lesko LJ, Zhao L. Kim H, et al. Among authors: trame mn. J Clin Pharmacol. 2019 Aug;59(8):1061-1069. doi: 10.1002/jcph.1380. Epub 2019 Feb 4. J Clin Pharmacol. 2019. PMID: 30716169 Clinical Trial.
36 results