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Number of nitrate groups determines reactivity and potency of organic nitrates: a proof of concept study in ALDH-2-/- mice.
Wenzel P, Hink U, Oelze M, Seeling A, Isse T, Bruns K, Steinhoff L, Brandt M, Kleschyov AL, Schulz E, Lange K, Weiner H, Lehmann J, Lackner KJ, Kawamoto T, Münzel T, Daiber A. Wenzel P, et al. Among authors: brandt m. Br J Pharmacol. 2007 Feb;150(4):526-33. doi: 10.1038/sj.bjp.0707116. Epub 2007 Jan 15. Br J Pharmacol. 2007. PMID: 17220910 Free PMC article.
Angiotensin II-induced vascular dysfunction depends on interferon-γ-driven immune cell recruitment and mutual activation of monocytes and NK-cells.
Kossmann S, Schwenk M, Hausding M, Karbach SH, Schmidgen MI, Brandt M, Knorr M, Hu H, Kröller-Schön S, Schönfelder T, Grabbe S, Oelze M, Daiber A, Münzel T, Becker C, Wenzel P. Kossmann S, et al. Among authors: brandt m. Arterioscler Thromb Vasc Biol. 2013 Jun;33(6):1313-9. doi: 10.1161/ATVBAHA.113.301437. Epub 2013 Mar 21. Arterioscler Thromb Vasc Biol. 2013. PMID: 23520167
Inflammatory monocytes determine endothelial nitric-oxide synthase uncoupling and nitro-oxidative stress induced by angiotensin II.
Kossmann S, Hu H, Steven S, Schönfelder T, Fraccarollo D, Mikhed Y, Brähler M, Knorr M, Brandt M, Karbach SH, Becker C, Oelze M, Bauersachs J, Widder J, Münzel T, Daiber A, Wenzel P. Kossmann S, et al. Among authors: brandt m. J Biol Chem. 2014 Oct 3;289(40):27540-50. doi: 10.1074/jbc.M114.604231. Epub 2014 Aug 20. J Biol Chem. 2014. PMID: 25143378 Free PMC article.
Heme oxygenase-1 suppresses a pro-inflammatory phenotype in monocytes and determines endothelial function and arterial hypertension in mice and humans.
Wenzel P, Rossmann H, Müller C, Kossmann S, Oelze M, Schulz A, Arnold N, Simsek C, Lagrange J, Klemz R, Schönfelder T, Brandt M, Karbach SH, Knorr M, Finger S, Neukirch C, Häuser F, Beutel ME, Kröller-Schön S, Schulz E, Schnabel RB, Lackner K, Wild PS, Zeller T, Daiber A, Blankenberg S, Münzel T. Wenzel P, et al. Among authors: brandt m. Eur Heart J. 2015 Dec 21;36(48):3437-46. doi: 10.1093/eurheartj/ehv544. Epub 2015 Oct 29. Eur Heart J. 2015. PMID: 26516175
Gut Microbiota Promote Angiotensin II-Induced Arterial Hypertension and Vascular Dysfunction.
Karbach SH, Schönfelder T, Brandão I, Wilms E, Hörmann N, Jäckel S, Schüler R, Finger S, Knorr M, Lagrange J, Brandt M, Waisman A, Kossmann S, Schäfer K, Münzel T, Reinhardt C, Wenzel P. Karbach SH, et al. Among authors: brandt m. J Am Heart Assoc. 2016 Aug 30;5(9):e003698. doi: 10.1161/JAHA.116.003698. J Am Heart Assoc. 2016. PMID: 27577581 Free PMC article.
1,657 results