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Page 1
Interaction of N-methyl-2-alkenyl-4-quinolones with ATP-dependent MurE ligase of Mycobacterium tuberculosis: antibacterial activity, molecular docking and inhibition kinetics.
Guzman JD, Wube A, Evangelopoulos D, Gupta A, Hüfner A, Basavannacharya C, Rahman MM, Thomaschitz C, Bauer R, McHugh TD, Nobeli I, Prieto JM, Gibbons S, Bucar F, Bhakta S. Guzman JD, et al. Among authors: mchugh td. J Antimicrob Chemother. 2011 Aug;66(8):1766-72. doi: 10.1093/jac/dkr203. Epub 2011 May 28. J Antimicrob Chemother. 2011. PMID: 21622974 Free PMC article.
Molecular bacterial load assay, a culture-free biomarker for rapid and accurate quantification of sputum Mycobacterium tuberculosis bacillary load during treatment.
Honeyborne I, McHugh TD, Phillips PP, Bannoo S, Bateson A, Carroll N, Perrin FM, Ronacher K, Wright L, van Helden PD, Walzl G, Gillespie SH. Honeyborne I, et al. Among authors: mchugh td. J Clin Microbiol. 2011 Nov;49(11):3905-11. doi: 10.1128/JCM.00547-11. Epub 2011 Sep 7. J Clin Microbiol. 2011. PMID: 21900522 Free PMC article.
The molecular bacterial load assay replaces solid culture for measuring early bactericidal response to antituberculosis treatment.
Honeyborne I, Mtafya B, Phillips PP, Hoelscher M, Ntinginya EN, Kohlenberg A, Rachow A, Rojas-Ponce G, McHugh TD, Heinrich N; Pan African Consortium for the Evaluation of Anti-tuberculosis Antibiotics. Honeyborne I, et al. Among authors: mchugh td. J Clin Microbiol. 2014 Aug;52(8):3064-7. doi: 10.1128/JCM.01128-14. Epub 2014 May 28. J Clin Microbiol. 2014. PMID: 24871215 Free PMC article.
Standardization of Nucleic Acid Tests for Clinical Measurements of Bacteria and Viruses.
Pavšič J, Devonshire AS, Parkes H, Schimmel H, Foy CA, Karczmarczyk M, Gutiérrez-Aguirre I, Honeyborne I, Huggett JF, McHugh TD, Milavec M, Zeichhardt H, Žel J. Pavšič J, et al. Among authors: mchugh td. J Clin Microbiol. 2015 Jul;53(7):2008-14. doi: 10.1128/JCM.02136-14. Epub 2014 Nov 12. J Clin Microbiol. 2015. PMID: 25392365 Free PMC article. Review.
Effective anti-tuberculosis therapy correlates with plasma small RNA.
Honeyborne I, Lipman MC, Eckold C, Evangelopoulos D, Gillespie SH, Pym A, McHugh TD. Honeyborne I, et al. Among authors: mchugh td. Eur Respir J. 2015 Jun;45(6):1741-4. doi: 10.1183/09031936.00221214. Epub 2015 Mar 5. Eur Respir J. 2015. PMID: 25745052 Free article. No abstract available.
Improving the tuberculosis drug development pipeline.
Evangelopoulos D, McHugh TD. Evangelopoulos D, et al. Among authors: mchugh td. Chem Biol Drug Des. 2015 Nov;86(5):951-60. doi: 10.1111/cbdd.12549. Epub 2015 Mar 28. Chem Biol Drug Des. 2015. PMID: 25772393 Review.
247 results