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Target 2035 - update on the quest for a probe for every protein.
Müller S, Ackloo S, Al Chawaf A, Al-Lazikani B, Antolin A, Baell JB, Beck H, Beedie S, Betz UAK, Bezerra GA, Brennan PE, Brown D, Brown PJ, Bullock AN, Carter AJ, Chaikuad A, Chaineau M, Ciulli A, Collins I, Dreher J, Drewry D, Edfeldt K, Edwards AM, Egner U, Frye SV, Fuchs SM, Hall MD, Hartung IV, Hillisch A, Hitchcock SH, Homan E, Kannan N, Kiefer JR, Knapp S, Kostic M, Kubicek S, Leach AR, Lindemann S, Marsden BD, Matsui H, Meier JL, Merk D, Michel M, Morgan MR, Mueller-Fahrnow A, Owen DR, Perry BG, Rosenberg SH, Saikatendu KS, Schapira M, Scholten C, Sharma S, Simeonov A, Sundström M, Superti-Furga G, Todd MH, Tredup C, Vedadi M, von Delft F, Willson TM, Winter GE, Workman P, Arrowsmith CH. Müller S, et al. Among authors: fuchs sm. RSC Med Chem. 2021 Dec 3;13(1):13-21. doi: 10.1039/d1md00228g. eCollection 2022 Jan 27. RSC Med Chem. 2021. PMID: 35211674 Free PMC article.
Association of UHRF1 with methylated H3K9 directs the maintenance of DNA methylation.
Rothbart SB, Krajewski K, Nady N, Tempel W, Xue S, Badeaux AI, Barsyte-Lovejoy D, Martinez JY, Bedford MT, Fuchs SM, Arrowsmith CH, Strahl BD. Rothbart SB, et al. Among authors: fuchs sm. Nat Struct Mol Biol. 2012 Nov;19(11):1155-60. doi: 10.1038/nsmb.2391. Epub 2012 Sep 30. Nat Struct Mol Biol. 2012. PMID: 23022729 Free PMC article.
Protein modifications in transcription elongation.
Fuchs SM, Laribee RN, Strahl BD. Fuchs SM, et al. Biochim Biophys Acta. 2009 Jan;1789(1):26-36. doi: 10.1016/j.bbagrm.2008.07.008. Epub 2008 Jul 30. Biochim Biophys Acta. 2009. PMID: 18718879 Free PMC article. Review.
Peptide microarrays to interrogate the "histone code".
Rothbart SB, Krajewski K, Strahl BD, Fuchs SM. Rothbart SB, et al. Among authors: fuchs sm. Methods Enzymol. 2012;512:107-35. doi: 10.1016/B978-0-12-391940-3.00006-8. Methods Enzymol. 2012. PMID: 22910205 Free PMC article.
The Ccr4-Not complex interacts with the mRNA export machinery.
Kerr SC, Azzouz N, Fuchs SM, Collart MA, Strahl BD, Corbett AH, Laribee RN. Kerr SC, et al. Among authors: fuchs sm. PLoS One. 2011 Mar 28;6(3):e18302. doi: 10.1371/journal.pone.0018302. PLoS One. 2011. PMID: 21464899 Free PMC article.
78 results