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Page 1
Functional screen of inflammatory bowel disease genes reveals key epithelial functions.
Ntunzwenimana JC, Boucher G, Paquette J, Gosselin H, Alikashani A, Morin N, Beauchamp C, Thauvette L, Rivard MÈ, Dupuis F, Deschênes S, Foisy S, Latour F, Lavallée G, Daly MJ, Xavier RJ; iGenoMed Consortium; Charron G, Goyette P, Rioux JD. Ntunzwenimana JC, et al. Among authors: charron g. Genome Med. 2021 Nov 11;13(1):181. doi: 10.1186/s13073-021-00996-7. Genome Med. 2021. PMID: 34758847 Free PMC article.
C1orf106 is a colitis risk gene that regulates stability of epithelial adherens junctions.
Mohanan V, Nakata T, Desch AN, Lévesque C, Boroughs A, Guzman G, Cao Z, Creasey E, Yao J, Boucher G, Charron G, Bhan AK, Schenone M, Carr SA, Reinecker HC, Daly MJ, Rioux JD, Lassen KG, Xavier RJ. Mohanan V, et al. Among authors: charron g. Science. 2018 Mar 9;359(6380):1161-1166. doi: 10.1126/science.aan0814. Epub 2018 Feb 1. Science. 2018. PMID: 29420262 Free PMC article.
Specific targeting of the IL-23 receptor, using a novel small peptide noncompetitive antagonist, decreases the inflammatory response.
Quiniou C, Domínguez-Punaro M, Cloutier F, Erfani A, Ennaciri J, Sivanesan D, Sanchez M, Chognard G, Hou X, Rivera JC, Beauchamp C, Charron G, Vilquin M, Kuchroo V, Michnick S, Rioux JD, Lesage S, Chemtob S. Quiniou C, et al. Among authors: charron g. Am J Physiol Regul Integr Comp Physiol. 2014 Nov 15;307(10):R1216-30. doi: 10.1152/ajpregu.00540.2013. Epub 2014 Aug 20. Am J Physiol Regul Integr Comp Physiol. 2014. PMID: 25354400 Free article.
Serum Analyte Profiles Associated With Crohn's Disease and Disease Location.
Boucher G, Paradis A, Chabot-Roy G, Coderre L, Hillhouse EE, Bitton A, Des Rosiers C, Levings MK, Schumm LP, Lazarev M, Brant SR, Duerr R, McGovern D, Silverberg MS, Cho J, Lesage S, Rioux JD; iGenoMed Consortium; NIDDK IBD Genetics Consortium. Boucher G, et al. Inflamm Bowel Dis. 2022 Jan 5;28(1):9-20. doi: 10.1093/ibd/izab123. Inflamm Bowel Dis. 2022. PMID: 34106269 Free PMC article.
Loss of hepatic LRPPRC alters mitochondrial bioenergetics, regulation of permeability transition and trans-membrane ROS diffusion.
Cuillerier A, Honarmand S, Cadete VJJ, Ruiz M, Forest A, Deschênes S, Beauchamp C; LSFC Consortium; Charron G, Rioux JD, Des Rosiers C, Shoubridge EA, Burelle Y. Cuillerier A, et al. Among authors: charron g. Hum Mol Genet. 2017 Aug 15;26(16):3186-3201. doi: 10.1093/hmg/ddx202. Hum Mol Genet. 2017. PMID: 28575497 Free PMC article.
Post-translational modifications, a key process in CD36 function: lessons from the spontaneously hypertensive rat heart.
Lauzier B, Merlen C, Vaillant F, McDuff J, Bouchard B, Beguin PC, Dolinsky VW, Foisy S, Villeneuve LR, Labarthe F, Dyck JR, Allen BG, Charron G, Des Rosiers C. Lauzier B, et al. Among authors: charron g. J Mol Cell Cardiol. 2011 Jul;51(1):99-108. doi: 10.1016/j.yjmcc.2011.04.001. Epub 2011 Apr 13. J Mol Cell Cardiol. 2011. PMID: 21510957
The dichotomous pattern of IL-12r and IL-23R expression elucidates the role of IL-12 and IL-23 in inflammation.
Chognard G, Bellemare L, Pelletier AN, Dominguez-Punaro MC, Beauchamp C, Guyon MJ, Charron G, Morin N, Sivanesan D, Kuchroo V, Xavier R, Michnick SW, Chemtob S, Rioux JD, Lesage S. Chognard G, et al. Among authors: charron g. PLoS One. 2014 Feb 21;9(2):e89092. doi: 10.1371/journal.pone.0089092. eCollection 2014. PLoS One. 2014. PMID: 24586521 Free PMC article.
118 results