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Page 1
Novel endosomolytic compounds enable highly potent delivery of antisense oligonucleotides.
Bost JP, Ojansivu M, Munson MJ, Wesén E, Gallud A, Gupta D, Gustafsson O, Saher O, Rädler J, Higgins SG, Lehto T, Holme MN, Dahlén A, Engkvist O, Strömstedt PE, Andersson S, Edvard Smith CI, Stevens MM, Esbjörner EK, Collén A, El Andaloussi S. Bost JP, et al. Commun Biol. 2022 Mar 1;5(1):185. doi: 10.1038/s42003-022-03132-2. Commun Biol. 2022. PMID: 35233031 Free PMC article.
Quantification of extracellular vesicles in vitro and in vivo using sensitive bioluminescence imaging.
Gupta D, Liang X, Pavlova S, Wiklander OPB, Corso G, Zhao Y, Saher O, Bost J, Zickler AM, Piffko A, Maire CL, Ricklefs FL, Gustafsson O, Llorente VC, Gustafsson MO, Bostancioglu RB, Mamand DR, Hagey DW, Görgens A, Nordin JZ, El Andaloussi S. Gupta D, et al. J Extracell Vesicles. 2020 Aug 21;9(1):1800222. doi: 10.1080/20013078.2020.1800222. J Extracell Vesicles. 2020. PMID: 32944187 Free PMC article.
Novel Orthogonally Hydrocarbon-Modified Cell-Penetrating Peptide Nanoparticles Mediate Efficient Delivery of Splice-Switching Antisense Oligonucleotides In Vitro and In Vivo.
Bazaz S, Lehto T, Tops R, Gissberg O, Gupta D, Bestas B, Bost J, Wiklander OPB, Sork H, Zaghloul EM, Mamand DR, Hällbrink M, Sillard R, Saher O, Ezzat K, Smith CIE, Andaloussi SE, Lehto T. Bazaz S, et al. Biomedicines. 2021 Aug 19;9(8):1046. doi: 10.3390/biomedicines9081046. Biomedicines. 2021. PMID: 34440250 Free PMC article.
Antibody-displaying extracellular vesicles for targeted cancer therapy.
Wiklander OPB, Mamand DR, Mohammad DK, Zheng W, Jawad Wiklander R, Sych T, Zickler AM, Liang X, Sharma H, Lavado A, Bost J, Roudi S, Corso G, Lennaárd AJ, Abedi-Valugerdi M, Mäger I, Alici E, Sezgin E, Nordin JZ, Gupta D, Görgens A, El Andaloussi S. Wiklander OPB, et al. Nat Biomed Eng. 2024 May 20. doi: 10.1038/s41551-024-01214-6. Online ahead of print. Nat Biomed Eng. 2024. PMID: 38769158
Lipid-based Transfection Reagents Exhibit Cryo-induced Increase in Transfection Efficiency.
Sork H, Nordin JZ, Turunen JJ, Wiklander OP, Bestas B, Zaghloul EM, Margus H, Padari K, Duru AD, Corso G, Bost J, Vader P, Pooga M, Smith CE, Wood MJ, Schiffelers RM, Hällbrink M, Andaloussi SE. Sork H, et al. Mol Ther Nucleic Acids. 2016 Mar 8;5(3):e290. doi: 10.1038/mtna.2016.8. Mol Ther Nucleic Acids. 2016. PMID: 27111416 Free PMC article.