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Age-associated decline of MondoA drives cellular senescence through impaired autophagy and mitochondrial homeostasis.
Yamamoto-Imoto H, Minami S, Shioda T, Yamashita Y, Sakai S, Maeda S, Yamamoto T, Oki S, Takashima M, Yamamuro T, Yanagawa K, Edahiro R, Iwatani M, So M, Tokumura A, Abe T, Imamura R, Nonomura N, Okada Y, Ayer DE, Ogawa H, Hara E, Takabatake Y, Isaka Y, Nakamura S, Yoshimori T. Yamamoto-Imoto H, et al. Among authors: hara e. Cell Rep. 2022 Mar 1;38(9):110444. doi: 10.1016/j.celrep.2022.110444. Cell Rep. 2022. PMID: 35235784 Free article.
Cellular Senescence: Defining a Path Forward.
Gorgoulis V, Adams PD, Alimonti A, Bennett DC, Bischof O, Bishop C, Campisi J, Collado M, Evangelou K, Ferbeyre G, Gil J, Hara E, Krizhanovsky V, Jurk D, Maier AB, Narita M, Niedernhofer L, Passos JF, Robbins PD, Schmitt CA, Sedivy J, Vougas K, von Zglinicki T, Zhou D, Serrano M, Demaria M. Gorgoulis V, et al. Among authors: hara e. Cell. 2019 Oct 31;179(4):813-827. doi: 10.1016/j.cell.2019.10.005. Cell. 2019. PMID: 31675495 Free article. Review.
SARS-CoV-2 infection triggers paracrine senescence and leads to a sustained senescence-associated inflammatory response.
Tsuji S, Minami S, Hashimoto R, Konishi Y, Suzuki T, Kondo T, Sasai M, Torii S, Ono C, Shichinohe S, Sato S, Wakita M, Okumura S, Nakano S, Matsudaira T, Matsumoto T, Kawamoto S, Yamamoto M, Watanabe T, Matsuura Y, Takayama K, Kobayashi T, Okamoto T, Hara E. Tsuji S, et al. Among authors: hara e. Nat Aging. 2022 Feb;2(2):115-124. doi: 10.1038/s43587-022-00170-7. Epub 2022 Jan 25. Nat Aging. 2022. PMID: 37117754 Free PMC article.
B cell senescence promotes age-related changes in oral microbiota.
Mizuno H, Kawamoto S, Uemura K, Park JH, Hori N, Okumura Y, Konishi Y, Hara E. Mizuno H, et al. Among authors: hara e. Aging Cell. 2024 Aug 9:e14304. doi: 10.1111/acel.14304. Online ahead of print. Aging Cell. 2024. PMID: 39123277 Free article.
356 results