Unwin R - Search Results

1

Glomerulonephritis and autoimmune vasculitis are independent of P2RX7 but may depend on alternative inflammasome pathways.

Prendecki M, McAdoo SP, Turner-Stokes T, Garcia-Diaz A, Orriss I, Woollard KJ, Behmoaras J, Cook HT, Unwin R, Pusey CD, Aitman TJ, Tam FW. Prendecki M, et al. Among authors: unwin r. J Pathol. 2022 Jul;257(3):300-313. doi: 10.1002/path.5890. Epub 2022 May 2. J Pathol. 2022. PMID: 35239186 Free PMC article.

2

Increased expression of the pro-apoptotic ATP-sensitive P2X7 receptor in experimental and human glomerulonephritis.

Turner CM, Tam FW, Lai PC, Tarzi RM, Burnstock G, Pusey CD, Cook HT, Unwin RJ. Turner CM, et al. Nephrol Dial Transplant. 2007 Feb;22(2):386-95. doi: 10.1093/ndt/gfl589. Epub 2006 Oct 13. Nephrol Dial Transplant. 2007. PMID: 17040997

3

P2X7 deficiency attenuates renal injury in experimental glomerulonephritis.

Taylor SR, Turner CM, Elliott JI, McDaid J, Hewitt R, Smith J, Pickering MC, Whitehouse DL, Cook HT, Burnstock G, Pusey CD, Unwin RJ, Tam FW. Taylor SR, et al. Among authors: unwin rj. J Am Soc Nephrol. 2009 Jun;20(6):1275-81. doi: 10.1681/ASN.2008060559. Epub 2009 Apr 23. J Am Soc Nephrol. 2009. PMID: 19389853 Free PMC article.

4

Sodium and water handling after gastric bypass surgery in a rat model.

Bueter M, Ashrafian H, Frankel AH, Tam FW, Unwin RJ, le Roux CW. Bueter M, et al. Surg Obes Relat Dis. 2011 Jan-Feb;7(1):68-73. doi: 10.1016/j.soard.2010.03.286. Epub 2010 Apr 1. Surg Obes Relat Dis. 2011. PMID: 20570570 Free PMC article.

5

A potential therapeutic role for P2X7 receptor (P2X7R) antagonists in the treatment of inflammatory diseases.

Arulkumaran N, Unwin RJ, Tam FW. Arulkumaran N, et al. Expert Opin Investig Drugs. 2011 Jul;20(7):897-915. doi: 10.1517/13543784.2011.578068. Epub 2011 Apr 21. Expert Opin Investig Drugs. 2011. PMID: 21510825 Free PMC article. Review.

6

P2 purinoceptors: Renal pathophysiology and therapeutic potential.

Booth JW, Tam FW, Unwin RJ. Booth JW, et al. Among authors: unwin rj. Clin Nephrol. 2012 Aug;78(2):154-63. doi: 10.5414/cn107325. Clin Nephrol. 2012. PMID: 22790461 Review.

7

P2X7 receptor-mediated Nlrp3-inflammasome activation is a genetic determinant of macrophage-dependent crescentic glomerulonephritis.

Deplano S, Cook HT, Russell R, Franchi L, Schneiter S, Bhangal G, Unwin RJ, Pusey CD, Tam FW, Behmoaras J. Deplano S, et al. Among authors: unwin rj. J Leukoc Biol. 2013 Jan;93(1):127-34. doi: 10.1189/jlb.0612284. Epub 2012 Oct 22. J Leukoc Biol. 2013. PMID: 23089744 Free article.

8

ATP and arterial calcification.

Fish RS, Klootwijk E, Tam FW, Kleta R, Wheeler DC, Unwin RJ, Norman J. Fish RS, et al. Among authors: unwin rj. Eur J Clin Invest. 2013 Apr;43(4):405-12. doi: 10.1111/eci.12055. Epub 2013 Feb 10. Eur J Clin Invest. 2013. PMID: 23398250 Review.

9

Is the inflammasome a potential therapeutic target in renal disease?

Turner CM, Arulkumaran N, Singer M, Unwin RJ, Tam FW. Turner CM, et al. BMC Nephrol. 2014 Jan 23;15:21. doi: 10.1186/1471-2369-15-21. BMC Nephrol. 2014. PMID: 24450291 Free PMC article.

10

Exaggerated renal fibrosis in P2X4 receptor-deficient mice following unilateral ureteric obstruction.

Kim MJ, Turner CM, Hewitt R, Smith J, Bhangal G, Pusey CD, Unwin RJ, Tam FW. Kim MJ, et al. Among authors: unwin rj. Nephrol Dial Transplant. 2014 Jul;29(7):1350-61. doi: 10.1093/ndt/gfu019. Epub 2014 Feb 25. Nephrol Dial Transplant. 2014. PMID: 24574541 Free PMC article.

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