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Human biliary epithelial cells from discarded donor livers rescue bile duct structure and function in a mouse model of biliary disease.
Hallett JM, Ferreira-Gonzalez S, Man TY, Kilpatrick AM, Esser H, Thirlwell K, Macmillan MT, Rodrigo-Torres D, Dwyer BJ, Gadd VL, Ashmore-Harris C, Lu WY, Thomson JP, Jansen MA, O'Duibhir E, Starkey Lewis PJ, Campana L, Aird RE, Bate TSR, Fraser AR, Campbell JDM, Oniscu GC, Hay DC, Callanan A, Forbes SJ. Hallett JM, et al. Among authors: macmillan mt. Cell Stem Cell. 2022 Mar 3;29(3):355-371.e10. doi: 10.1016/j.stem.2022.02.006. Cell Stem Cell. 2022. PMID: 35245467 Free PMC article.
Cell therapy for advanced liver diseases: Repair or rebuild.
Dwyer BJ, Macmillan MT, Brennan PN, Forbes SJ. Dwyer BJ, et al. Among authors: macmillan mt. J Hepatol. 2021 Jan;74(1):185-199. doi: 10.1016/j.jhep.2020.09.014. Epub 2020 Sep 22. J Hepatol. 2021. PMID: 32976865 Review.
Study protocol: a multicentre, open-label, parallel-group, phase 2, randomised controlled trial of autologous macrophage therapy for liver cirrhosis (MATCH).
Brennan PN, MacMillan M, Manship T, Moroni F, Glover A, Graham C, Semple S, Morris DM, Fraser AR, Pass C, McGowan NWA, Turner ML, Lachlan N, Dillon JF, Campbell JDM, Fallowfield JA, Forbes SJ. Brennan PN, et al. BMJ Open. 2021 Nov 8;11(11):e053190. doi: 10.1136/bmjopen-2021-053190. BMJ Open. 2021. PMID: 34750149 Free PMC article.
Senolytic treatment preserves biliary regenerative capacity lost through cellular senescence during cold storage.
Ferreira-Gonzalez S, Man TY, Esser H, Aird R, Kilpatrick AM, Rodrigo-Torres D, Younger N, Campana L, Gadd VL, Dwyer B, Aleksieva N, Boulter L, Macmillan MT, Wang Y, Mylonas KJ, Ferenbach DA, Kendall TJ, Lu WY, Acosta JC, Kurian D, O'Neill S, Oniscu GC, Banales JM, Krimpenfort PJ, Forbes SJ. Ferreira-Gonzalez S, et al. Among authors: macmillan mt. Sci Transl Med. 2022 Dec 7;14(674):eabj4375. doi: 10.1126/scitranslmed.abj4375. Epub 2022 Dec 7. Sci Transl Med. 2022. PMID: 36475903
Host hepatocyte senescence determines the success of hepatocyte transplantation in a mouse model of liver injury.
Gadd VL, Ferreira-Gonzalez S, Man TY, Kilpatrick AM, Aird RE, Smith IP, Rodrigo-Torres D, Kurian D, Hallett JM, Ashmore-Harris C, Esser H, Ferreira MF, Macmillan MT, Lu WY, Forbes SJ. Gadd VL, et al. Among authors: macmillan mt. J Hepatol. 2025 Jan 2:S0168-8278(24)02830-7. doi: 10.1016/j.jhep.2024.12.039. Online ahead of print. J Hepatol. 2025. PMID: 39755157 Free article.
Autologous macrophage therapy for liver cirrhosis: a phase 2 open-label randomized controlled trial.
Brennan PN, MacMillan M, Manship T, Moroni F, Glover A, Troland D, MacPherson I, Graham C, Aird R, Semple SIK, Morris DM, Fraser AR, Pass C, McGowan NWA, Turner ML, Manson L, Lachlan NJ, Dillon JF, Kilpatrick AM, Campbell JDM, Fallowfield JA, Forbes SJ. Brennan PN, et al. Nat Med. 2025 Jan 10. doi: 10.1038/s41591-024-03406-8. Online ahead of print. Nat Med. 2025. PMID: 39794616
Incidental Non-cardiac Findings in Cardiovascular Imaging.
Macmillan MT, Williams MC. Macmillan MT, et al. Curr Treat Options Cardiovasc Med. 2018 Oct 23;20(12):93. doi: 10.1007/s11936-018-0700-5. Curr Treat Options Cardiovasc Med. 2018. PMID: 30353401 Free PMC article. Review.
15 results