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Endogenous ADAR-mediated RNA editing in non-human primates using stereopure chemically modified oligonucleotides.
Monian P, Shivalila C, Lu G, Shimizu M, Boulay D, Bussow K, Byrne M, Bezigian A, Chatterjee A, Chew D, Desai J, Favaloro F, Godfrey J, Hoss A, Iwamoto N, Kawamoto T, Kumarasamy J, Lamattina A, Lindsey A, Liu F, Looby R, Marappan S, Metterville J, Murphy R, Rossi J, Pu T, Bhattarai B, Standley S, Tripathi S, Yang H, Yin Y, Yu H, Zhou C, Apponi LH, Kandasamy P, Vargeese C. Monian P, et al. Among authors: yu h. Nat Biotechnol. 2022 Jul;40(7):1093-1102. doi: 10.1038/s41587-022-01225-1. Epub 2022 Mar 7. Nat Biotechnol. 2022. PMID: 35256816
Impact of stereopure chimeric backbone chemistries on the potency and durability of gene silencing by RNA interference.
Liu W, Iwamoto N, Marappan S, Luu K, Tripathi S, Purcell-Estabrook E, Shelke JD, Shah H, Lamattina A, Pan Q, Schrand B, Favaloro F, Bedekar M, Chatterjee A, Desai J, Kawamoto T, Lu G, Metterville J, Samaraweera M, Prakasha PS, Yang H, Yin Y, Yu H, Giangrande PH, Byrne M, Kandasamy P, Vargeese C. Liu W, et al. Among authors: yu h. Nucleic Acids Res. 2023 May 22;51(9):4126-4147. doi: 10.1093/nar/gkad268. Nucleic Acids Res. 2023. PMID: 37070173 Free PMC article.
Rational design of base, sugar and backbone modifications improves ADAR-mediated RNA editing.
Lu G, Shivalila C, Monian P, Yu H, Harding I, Briem S, Byrne M, Faraone A, Friend S, Huth O, Iwamoto N, Kawamoto T, Kumarasamy J, Lamattina A, Longo K, McCarthy L, McGlynn A, Molski A, Pan Q, Pu T, Purcell-Estabrook E, Rossi J, Standley S, Thomas C, Walen A, Yang H, Kandasamy P, Vargeese C. Lu G, et al. Among authors: yu h. Nucleic Acids Res. 2024 Sep 23;52(17):10068-10084. doi: 10.1093/nar/gkae681. Nucleic Acids Res. 2024. PMID: 39149897 Free PMC article.
FoxO6 and PGC-1α form a regulatory loop in myogenic cells.
Chung SY, Huang WC, Su CW, Lee KW, Chi HC, Lin CT, Chen ST, Huang KM, Tsai MS, Yu HP, Chen SL. Chung SY, et al. Biosci Rep. 2013 Jun 13;33(3):e00045. doi: 10.1042/BSR20130031. Biosci Rep. 2013. PMID: 23639108 Free PMC article.
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