Berríos KN - Search Results

1

The Base-Editing Enzyme APOBEC3A Catalyzes Cytosine Deamination in RNA with Low Proficiency and High Selectivity.

Barka A, Berríos KN, Bailer P, Schutsky EK, Wang T, Kohli RM. Barka A, et al. Among authors: berrios kn. ACS Chem Biol. 2022 Mar 18;17(3):629-636. doi: 10.1021/acschembio.1c00919. Epub 2022 Mar 9. ACS Chem Biol. 2022. PMID: 35262324 Free PMC article.

2

Harnessing natural DNA modifying activities for editing of the genome and epigenome.

DeNizio JE, Schutsky EK, Berrios KN, Liu MY, Kohli RM. DeNizio JE, et al. Among authors: berrios kn. Curr Opin Chem Biol. 2018 Aug;45:10-17. doi: 10.1016/j.cbpa.2018.01.016. Epub 2018 Feb 13. Curr Opin Chem Biol. 2018. PMID: 29452938 Free PMC article. Review.

3

Bisulfite-Free Sequencing of 5-Hydroxymethylcytosine with APOBEC-Coupled Epigenetic Sequencing (ACE-Seq).

Wang T, Luo M, Berrios KN, Schutsky EK, Wu H, Kohli RM. Wang T, et al. Among authors: berrios kn. Methods Mol Biol. 2021;2198:349-367. doi: 10.1007/978-1-0716-0876-0_27. Methods Mol Biol. 2021. PMID: 32822044

4

Controllable genome editing with split-engineered base editors.

Berríos KN, Evitt NH, DeWeerd RA, Ren D, Luo M, Barka A, Wang T, Bartman CR, Lan Y, Green AM, Shi J, Kohli RM. Berríos KN, et al. Nat Chem Biol. 2021 Dec;17(12):1262-1270. doi: 10.1038/s41589-021-00880-w. Epub 2021 Oct 18. Nat Chem Biol. 2021. PMID: 34663942 Free PMC article.

5

Structure-Guided Design of a Potent and Specific Inhibitor against the Genomic Mutator APOBEC3A.

Serrano JC, von Trentini D, Berríos KN, Barka A, Dmochowski IJ, Kohli RM. Serrano JC, et al. Among authors: berrios kn. ACS Chem Biol. 2022 Dec 16;17(12):3379-3388. doi: 10.1021/acschembio.2c00796. Epub 2022 Dec 8. ACS Chem Biol. 2022. PMID: 36475588 Free PMC article.

6

Direct enzymatic sequencing of 5-methylcytosine at single-base resolution.

Wang T, Fowler JM, Liu L, Loo CE, Luo M, Schutsky EK, Berríos KN, DeNizio JE, Dvorak A, Downey N, Montermoso S, Pingul BY, Nasrallah M, Gosal WS, Wu H, Kohli RM. Wang T, et al. Among authors: berrios kn. Nat Chem Biol. 2023 Aug;19(8):1004-1012. doi: 10.1038/s41589-023-01318-1. Epub 2023 Jun 15. Nat Chem Biol. 2023. PMID: 37322153 Free PMC article.

7

N-(7-Cyano-6-(4-fluoro-3-(2-(3-(trifluoromethyl)phenyl)acetamido)phenoxy)benzo[d]thiazol-2-yl)cyclopropanecarboxamide (TAK632) Promotes Inhibition of BRAF through the Induction of Inhibited Dimers.

Grasso M, Estrada MA, Berrios KN, Winkler JD, Marmorstein R. Grasso M, et al. Among authors: berrios kn. J Med Chem. 2018 Jun 14;61(11):5034-5046. doi: 10.1021/acs.jmedchem.8b00499. Epub 2018 May 18. J Med Chem. 2018. PMID: 29727562 Free PMC article.

8

Oral nitrite restores age-dependent phenotypes in eNOS-null mice.

Tenopoulou M, Doulias PT, Nakamoto K, Berrios K, Zura G, Li C, Faust M, Yakovishina V, Evans P, Tan L, Bennett MJ, Snyder NW, Quinn WJ 3rd, Baur JA, Atochin DN, Huang PL, Ischiropoulos H. Tenopoulou M, et al. JCI Insight. 2018 Aug 23;3(16):e122156. doi: 10.1172/jci.insight.122156. eCollection 2018 Aug 23. JCI Insight. 2018. PMID: 30135317 Free PMC article.

9

Cooperativity between Cas9 and hyperactive AID establishes broad and diversifying mutational footprints in base editors.

Berríos KN, Barka A, Gill J, Serrano JC, Bailer PF, Parker JB, Evitt NH, Gajula KS, Shi J, Kohli RM. Berríos KN, et al. Nucleic Acids Res. 2024 Feb 28;52(4):2078-2090. doi: 10.1093/nar/gkae024. Nucleic Acids Res. 2024. PMID: 38261989 Free PMC article.

10

Joint single-cell profiling resolves 5mC and 5hmC and reveals their distinct gene regulatory effects.

Fabyanic EB, Hu P, Qiu Q, Berríos KN, Connolly DR, Wang T, Flournoy J, Zhou Z, Kohli RM, Wu H. Fabyanic EB, et al. Among authors: berrios kn. Nat Biotechnol. 2024 Jun;42(6):960-974. doi: 10.1038/s41587-023-01909-2. Epub 2023 Aug 28. Nat Biotechnol. 2024. PMID: 37640946 Free PMC article.

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