Hammerschmidt SJ - Search Results

1

Identification, Characterization, and Synthesis of Natural Parasitic Cysteine Protease Inhibitors: Pentacitidins Are More Potent Falcitidin Analogues.

Brinkmann S, Semmler S, Kersten C, Patras MA, Kurz M, Fuchs N, Hammerschmidt SJ, Legac J, Hammann PE, Vilcinskas A, Rosenthal PJ, Schirmeister T, Bauer A, Schäberle TF. Brinkmann S, et al. Among authors: hammerschmidt sj. ACS Chem Biol. 2022 Mar 18;17(3):576-589. doi: 10.1021/acschembio.1c00861. Epub 2022 Mar 9. ACS Chem Biol. 2022. PMID: 35262340

2

Structure-Activity Relationships of Benzamides and Isoindolines Designed as SARS-CoV Protease Inhibitors Effective against SARS-CoV-2.

Welker A, Kersten C, Müller C, Madhugiri R, Zimmer C, Müller P, Zimmermann R, Hammerschmidt S, Maus H, Ziebuhr J, Sotriffer C, Schirmeister T. Welker A, et al. ChemMedChem. 2021 Jan 19;16(2):340-354. doi: 10.1002/cmdc.202000548. Epub 2020 Oct 16. ChemMedChem. 2021. PMID: 32930481 Free PMC article.

3

SARS-CoV-PL^pro-Inhibitoren als mögliche Breitspektrum-Virostatika.

Hammerschmidt SJ, Müller P, Schirmeister T. Hammerschmidt SJ, et al. Biospektrum (Heidelb). 2021;27(3):254-256. doi: 10.1007/s12268-021-1576-6. Epub 2021 May 11. Biospektrum (Heidelb). 2021. PMID: 33994673 Free PMC article. Review. German.

4

Interfering with Host Proteases in SARS-CoV-2 Entry as a Promising Therapeutic Strategy.

Müller P, Maus H, Hammerschmidt SJ, Knaff PM, Mailänder V, Schirmeister T, Kersten C. Müller P, et al. Among authors: hammerschmidt sj. Curr Med Chem. 2022;29(4):635-665. doi: 10.2174/0929867328666210526111318. Curr Med Chem. 2022. PMID: 34042026 Review.

5

A low-cost 3D-printable differential scanning fluorometer for protein and RNA melting experiments.

Barthels F, Hammerschmidt SJ, Fischer TR, Zimmer C, Kallert E, Helm M, Kersten C, Schirmeister T. Barthels F, et al. Among authors: hammerschmidt sj. HardwareX. 2022 Jan 7;11:e00256. doi: 10.1016/j.ohx.2022.e00256. eCollection 2022 Apr. HardwareX. 2022. PMID: 35509940 Free PMC article.

6

2-Sulfonylpyrimidines as Privileged Warheads for the Development of S. aureus Sortase A Inhibitors.

Barthels F, Meyr J, Hammerschmidt SJ, Marciniak T, Räder HJ, Ziebuhr W, Engels B, Schirmeister T. Barthels F, et al. Among authors: hammerschmidt sj. Front Mol Biosci. 2022 Jan 3;8:804970. doi: 10.3389/fmolb.2021.804970. eCollection 2021. Front Mol Biosci. 2022. PMID: 35047562 Free PMC article.

7

Proline-Based Allosteric Inhibitors of Zika and Dengue Virus NS2B/NS3 Proteases.

Millies B, von Hammerstein F, Gellert A, Hammerschmidt S, Barthels F, Göppel U, Immerheiser M, Elgner F, Jung N, Basic M, Kersten C, Kiefer W, Bodem J, Hildt E, Windbergs M, Hellmich UA, Schirmeister T. Millies B, et al. J Med Chem. 2019 Dec 26;62(24):11359-11382. doi: 10.1021/acs.jmedchem.9b01697. Epub 2019 Dec 13. J Med Chem. 2019. PMID: 31769670

8

Cis autocatalytic cleavage of glycine-linked Zika virus NS2B-NS3 protease constructs.

von Hammerstein F, Lauth LM, Hammerschmidt S, Wagner A, Schirmeister T, Hellmich UA. von Hammerstein F, et al. FEBS Lett. 2019 Aug;593(16):2204-2213. doi: 10.1002/1873-3468.13507. Epub 2019 Jul 9. FEBS Lett. 2019. PMID: 31240714 Free article.

9

SAR of novel benzothiazoles targeting an allosteric pocket of DENV and ZIKV NS2B/NS3 proteases.

Maus H, Barthels F, Hammerschmidt SJ, Kopp K, Millies B, Gellert A, Ruggieri A, Schirmeister T. Maus H, et al. Among authors: hammerschmidt sj. Bioorg Med Chem. 2021 Oct 1;47:116392. doi: 10.1016/j.bmc.2021.116392. Epub 2021 Sep 4. Bioorg Med Chem. 2021. PMID: 34509861

10

Lead Discovery of SARS-CoV-2 Main Protease Inhibitors through Covalent Docking-Based Virtual Screening.

Amendola G, Ettari R, Previti S, Di Chio C, Messere A, Di Maro S, Hammerschmidt SJ, Zimmer C, Zimmermann RA, Schirmeister T, Zappalà M, Cosconati S. Amendola G, et al. Among authors: hammerschmidt sj. J Chem Inf Model. 2021 Apr 26;61(4):2062-2073. doi: 10.1021/acs.jcim.1c00184. Epub 2021 Mar 30. J Chem Inf Model. 2021. PMID: 33784094

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