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Dysregulation of the miRNome unveils a crosstalk between obesity and prostate cancer: miR-107 asa personalized diagnostic and therapeutic tool.
Herrero-Aguayo V, Sáez-Martínez P, Jiménez-Vacas JM, Moreno-Montilla MT, Montero-Hidalgo AJ, Pérez-Gómez JM, López-Canovas JL, Porcel-Pastrana F, Carrasco-Valiente J, Anglada FJ, Gómez-Gómez E, Yubero-Serrano EM, Ibañez-Costa A, Herrera-Martínez AD, Sarmento-Cabral A, Gahete MD, Luque RM. Herrero-Aguayo V, et al. Among authors: lopez canovas jl. Mol Ther Nucleic Acids. 2022 Feb 12;27:1164-1178. doi: 10.1016/j.omtn.2022.02.010. eCollection 2022 Mar 8. Mol Ther Nucleic Acids. 2022. PMID: 35282415 Free PMC article.
Influence of Obesity in the miRNome: miR-4454, a Key Regulator of Insulin Response Via Splicing Modulation in Prostate.
Herrero-Aguayo V, Jiménez-Vacas JM, Sáez-Martínez P, Gómez-Gómez E, López-Cánovas JL, Garrido-Sánchez L, Herrera-Martínez AD, García-Bermejo L, Macías-González M, López-Miranda J, Castaño JP, Gahete MD, Luque RM. Herrero-Aguayo V, et al. J Clin Endocrinol Metab. 2021 Jan 23;106(2):e469-e484. doi: 10.1210/clinem/dgaa580. J Clin Endocrinol Metab. 2021. PMID: 32841353
Dysregulation of splicing variants and spliceosome components in breast cancer.
Gahete MD, Herman-Sanchez N, Fuentes-Fayos AC, Lopez-Canovas JL, Luque RM. Gahete MD, et al. Among authors: lopez canovas jl. Endocr Relat Cancer. 2022 Aug 1;29(9):R123-R142. doi: 10.1530/ERC-22-0019. Print 2022 Sep 1. Endocr Relat Cancer. 2022. PMID: 35728261 Free article. Review.
Dysregulation of Components of the Inflammasome Machinery After Bariatric Surgery: Novel Targets for a Chronic Disease.
Herrero-Aguayo V, Sáez-Martínez P, López-Cánovas JL, Prados-Carmona JJ, Alcántara-Laguna MD, López FL, Molina-Puerta MJ, Calañas-Continente A, Membrives A, Castilla J, Ruiz-Ravelo J, Alonso-Echague R, Yubero-Serrano EM, Castaño JP, Gahete MD, Gálvez-Moreno MA, Luque RM, Herrera-Martínez AD. Herrero-Aguayo V, et al. Among authors: lopez canovas jl. J Clin Endocrinol Metab. 2021 Nov 19;106(12):e4917-e4934. doi: 10.1210/clinem/dgab586. J Clin Endocrinol Metab. 2021. PMID: 34363480
Splicing factor SF3B1 is overexpressed and implicated in the aggressiveness and survival of hepatocellular carcinoma.
López-Cánovas JL, Del Rio-Moreno M, García-Fernandez H, Jiménez-Vacas JM, Moreno-Montilla MT, Sánchez-Frias ME, Amado V, L-López F, Fondevila MF, Ciria R, Gómez-Luque I, Briceño J, Nogueiras R, de la Mata M, Castaño JP, Rodriguez-Perálvarez M, Luque RM, Gahete MD. López-Cánovas JL, et al. Cancer Lett. 2021 Jan 1;496:72-83. doi: 10.1016/j.canlet.2020.10.010. Epub 2020 Oct 8. Cancer Lett. 2021. PMID: 33038489
Signaling pathways in hepatocellular carcinoma.
Garcia-Lezana T, Lopez-Canovas JL, Villanueva A. Garcia-Lezana T, et al. Adv Cancer Res. 2021;149:63-101. doi: 10.1016/bs.acr.2020.10.002. Epub 2020 Nov 24. Adv Cancer Res. 2021. PMID: 33579428 Review.
Quantitative proteomic analysis unveils a critical role of VARS1 in hepatocellular carcinoma aggressiveness through the modulation of MAGI1 expression.
Hermán-Sánchez N, Del Rio-Moreno M, Ciria R, Sánchez-Frias ME, Fernández-Barrena MG, Uriarte I, Chicano-Galvez E, Ortea I, Peralbo-Molina Á, Briceño J, Avila MA, Rodríguez-Perálvarez M, Luque RM, López-Cánovas JL, Gahete MD. Hermán-Sánchez N, et al. Among authors: lopez canovas jl. Mol Cancer. 2025 Jan 14;24(1):15. doi: 10.1186/s12943-024-02206-5. Mol Cancer. 2025. PMID: 39810176 Free PMC article.
Aging Deteriorates Blood Brain Barrier Function and Polarizes Adaptive T Cell Expansion Contributing to Neurocognitive Damage in Experimental Cirrhosis.
Martínez-López S, García-Gutiérrez MS, Navarrete F, Gómez-Hurtado I, Zapater P, Ańgel E, Juanola O, López-Cánovas JL, Boix P, Hadid MC, Puig-Kröger A, Gahete MD, Manzanares J, Caparrós E, Francés R. Martínez-López S, et al. Among authors: lopez canovas jl. Aging Dis. 2024 Nov 23. doi: 10.14336/AD.2024.0932. Online ahead of print. Aging Dis. 2024. PMID: 39656486
Fecal microbiota transplantation, a tool to transfer healthy longevity.
Novelle MG, Naranjo-Martínez B, López-Cánovas JL, Díaz-Ruiz A. Novelle MG, et al. Among authors: lopez canovas jl. Ageing Res Rev. 2025 Jan;103:102585. doi: 10.1016/j.arr.2024.102585. Epub 2024 Nov 23. Ageing Res Rev. 2025. PMID: 39586550 Free article. Review.
The Exon Junction Complex component EIF4A3 plays a splicing-linked oncogenic role in pancreatic ductal adenocarcinoma.
Blázquez-Encinas R, Alors-Pérez E, Moreno-Montilla MT, García-Vioque V, Sánchez-Frías ME, Mafficini A, López-Cánovas JL, Bousquet C, Gahete MD, Lawlor RT, Luque RM, Scarpa A, Arjona-Sánchez Á, Pedraza-Arevalo S, Ibáñez-Costa A, Castaño JP. Blázquez-Encinas R, et al. Among authors: lopez canovas jl. Cancer Gene Ther. 2024 Nov;31(11):1646-1657. doi: 10.1038/s41417-024-00814-3. Epub 2024 Sep 4. Cancer Gene Ther. 2024. PMID: 39232176 Free PMC article.
13 results