Morio H - Search Results

1

In Vitro-In Vivo Correlation of Blood-Brain Barrier Permeability of Drugs: A Feasibility Study Towards Development of Prediction Methods for Brain Drug Concentration in Humans.

Ito R, Morio H, Baba T, Sakaguchi Y, Wakayama N, Isogai R, Yamaura Y, Komori T, Furihata T. Ito R, et al. Among authors: morio h. Pharm Res. 2022 Jul;39(7):1575-1586. doi: 10.1007/s11095-022-03189-y. Epub 2022 Mar 14. Pharm Res. 2022. PMID: 35288803

2

Development, Characterization and Potential Applications of a Multicellular Spheroidal Human Blood-Brain Barrier Model Integrating Three Conditionally Immortalized Cell Lines.

Kitamura K, Umehara K, Ito R, Yamaura Y, Komori T, Morio H, Akita H, Furihata T. Kitamura K, et al. Among authors: morio h. Biol Pharm Bull. 2021 Jul 1;44(7):984-991. doi: 10.1248/bpb.b21-00218. Epub 2021 Apr 24. Biol Pharm Bull. 2021. PMID: 33896887 Free article.

3

Human Immortalized Cell-Based Blood-Brain Barrier Spheroid Models Offer an Evaluation Tool for the Brain Penetration Properties of Macromolecules.

Kitamura K, Okamoto A, Morio H, Isogai R, Ito R, Yamaura Y, Izumi S, Komori T, Ito S, Ohtsuki S, Akita H, Furihata T. Kitamura K, et al. Among authors: morio h. Mol Pharm. 2022 Aug 1;19(8):2754-2764. doi: 10.1021/acs.molpharmaceut.2c00120. Epub 2022 Jun 29. Mol Pharm. 2022. PMID: 35766901

4

Generation of a Human Conditionally Immortalized Cell-based Multicellular Spheroidal Blood-Brain Barrier Model for Permeability Evaluation of Macromolecules.

Isogai R, Morio H, Okamoto A, Kitamura K, Furihata T. Isogai R, et al. Among authors: morio h. Bio Protoc. 2022 Aug 5;12(15):e4465. doi: 10.21769/BioProtoc.4465. eCollection 2022 Aug 5. Bio Protoc. 2022. PMID: 36082368 Free PMC article.

5

Differentiated HASTR/ci35 cells: A promising in vitro human astrocyte model for facilitating CNS drug development studies.

Kitamura K, Ito R, Umehara K, Morio H, Saito K, Suzuki S, Hashimoto M, Saito Y, Anzai N, Akita H, Chiba K, Furihata T. Kitamura K, et al. Among authors: morio h. J Pharmacol Sci. 2018 Aug;137(4):350-358. doi: 10.1016/j.jphs.2018.06.013. Epub 2018 Aug 9. J Pharmacol Sci. 2018. PMID: 30150146 Free article.

6

Differential inhibition features of direct-acting anti-hepatitis C virus agents against human organic anion transporting polypeptide 2B1.

Furihata T, Fu Z, Suzuki Y, Matsumoto S, Morio H, Tsubota A, Matsumoto S, Chiba K. Furihata T, et al. Among authors: morio h. Int J Antimicrob Agents. 2015 Oct;46(4):381-8. doi: 10.1016/j.ijantimicag.2015.05.013. Epub 2015 Jun 24. Int J Antimicrob Agents. 2015. PMID: 26163159

7

Human organic anion transporter 2 is an entecavir, but not tenofovir, transporter.

Furihata T, Morio H, Zhu M, Suzuki Y, Ide H, Tsubota A, Fu Z, Anzai N, Chiba K. Furihata T, et al. Among authors: morio h. Drug Metab Pharmacokinet. 2017 Feb;32(1):116-119. doi: 10.1016/j.dmpk.2016.09.004. Epub 2016 Sep 23. Drug Metab Pharmacokinet. 2017. PMID: 27916488

8

Development of a New Conditionally Immortalized Human Liver Sinusoidal Endothelial Cells.

Zhu M, Koibuchi A, Ide H, Morio H, Shibuya M, Kamiichi A, Tsubota A, Anzai N, Akita H, Chiba K, Furihata T. Zhu M, et al. Among authors: morio h. Biol Pharm Bull. 2018;41(3):440-444. doi: 10.1248/bpb.b17-00661. Biol Pharm Bull. 2018. PMID: 29491221 Free article.

9

Different Response Profiles of Gastrointestinal Cancer Cells to an L-Type Amino Acid Transporter Inhibitor, JPH203.

Muto Y, Furihata T, Kaneko M, Higuchi K, Okunushi K, Morio H, Reien Y, Uesato M, Matsubara H, Anzai N. Muto Y, et al. Among authors: morio h. Anticancer Res. 2019 Jan;39(1):159-165. doi: 10.21873/anticanres.13092. Anticancer Res. 2019. PMID: 30591453

10

Cancer-type organic anion transporting polypeptide 1B3 is a target for cancer suicide gene therapy using RNA trans-splicing technology.

Sun Y, Piñón Hofbauer J, Harada M, Wöss K, Koller U, Morio H, Stierschneider A, Kitamura K, Hashimoto M, Chiba K, Akita H, Anzai N, Reichelt J, Bauer JW, Guttmann-Gruber C, Furihata T. Sun Y, et al. Among authors: morio h. Cancer Lett. 2018 Oct 1;433:107-116. doi: 10.1016/j.canlet.2018.06.032. Epub 2018 Jun 27. Cancer Lett. 2018. PMID: 29960051

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