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Orally-active, clinically-translatable senolytics restore α-Klotho in mice and humans.
Zhu Y, Prata LGPL, Gerdes EOW, Netto JME, Pirtskhalava T, Giorgadze N, Tripathi U, Inman CL, Johnson KO, Xue A, Palmer AK, Chen T, Schaefer K, Justice JN, Nambiar AM, Musi N, Kritchevsky SB, Chen J, Khosla S, Jurk D, Schafer MJ, Tchkonia T, Kirkland JL. Zhu Y, et al. Among authors: justice jn. EBioMedicine. 2022 Mar;77:103912. doi: 10.1016/j.ebiom.2022.103912. Epub 2022 Mar 13. EBioMedicine. 2022. PMID: 35292270 Free PMC article.
Development of Clinical Trials to Extend Healthy Lifespan.
Justice JN, Niedernhofer L, Robbins PD, Aroda VR, Espeland MA, Kritchevsky SB, Kuchel GA, Barzilai N. Justice JN, et al. Cardiovasc Endocrinol Metab. 2018 Dec;7(4):80-83. doi: 10.1097/XCE.0000000000000159. Cardiovasc Endocrinol Metab. 2018. PMID: 30906924 Free PMC article.
Testing the Geroscience Hypothesis: Early Days.
Kritchevsky SB, Justice JN. Kritchevsky SB, et al. Among authors: justice jn. J Gerontol A Biol Sci Med Sci. 2020 Jan 1;75(1):99-101. doi: 10.1093/gerona/glz267. J Gerontol A Biol Sci Med Sci. 2020. PMID: 31834386 Free PMC article. No abstract available.
63 results