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The kinesin KIF4 mediates HBV/HDV entry through the regulation of surface NTCP localization and can be targeted by RXR agonists in vitro.
Gad SA, Sugiyama M, Tsuge M, Wakae K, Fukano K, Oshima M, Sureau C, Watanabe N, Kato T, Murayama A, Li Y, Shoji I, Shimotohno K, Chayama K, Muramatsu M, Wakita T, Nozaki T, Aly HH. Gad SA, et al. Among authors: sugiyama m. PLoS Pathog. 2022 Mar 21;18(3):e1009983. doi: 10.1371/journal.ppat.1009983. eCollection 2022 Mar. PLoS Pathog. 2022. PMID: 35312737 Free PMC article.
Cyclosporin A and its analogs inhibit hepatitis B virus entry into cultured hepatocytes through targeting a membrane transporter, sodium taurocholate cotransporting polypeptide (NTCP).
Watashi K, Sluder A, Daito T, Matsunaga S, Ryo A, Nagamori S, Iwamoto M, Nakajima S, Tsukuda S, Borroto-Esoda K, Sugiyama M, Tanaka Y, Kanai Y, Kusuhara H, Mizokami M, Wakita T. Watashi K, et al. Among authors: sugiyama m. Hepatology. 2014 May;59(5):1726-37. doi: 10.1002/hep.26982. Epub 2014 Apr 1. Hepatology. 2014. PMID: 24375637 Free PMC article.
Dysregulation of retinoic acid receptor diminishes hepatocyte permissiveness to hepatitis B virus infection through modulation of sodium taurocholate cotransporting polypeptide (NTCP) expression.
Tsukuda S, Watashi K, Iwamoto M, Suzuki R, Aizaki H, Okada M, Sugiyama M, Kojima S, Tanaka Y, Mizokami M, Li J, Tong S, Wakita T. Tsukuda S, et al. Among authors: sugiyama m. J Biol Chem. 2015 Feb 27;290(9):5673-84. doi: 10.1074/jbc.M114.602540. Epub 2014 Dec 30. J Biol Chem. 2015. PMID: 25550158 Free PMC article.
Seroprevalence of chronic hepatitis B, as determined from dried blood spots, among children and their mothers in central Lao People's Democratic Republic: a multistage, stratified cluster sampling survey.
Komada K, Sugiyama M, Vongphrachanh P, Xeuatvongsa A, Khamphaphongphane B, Kitamura T, Kiyohara T, Wakita T, Oshitani H, Hachiya M. Komada K, et al. Among authors: sugiyama m. Int J Infect Dis. 2015 Jul;36:21-6. doi: 10.1016/j.ijid.2015.04.020. Epub 2015 May 6. Int J Infect Dis. 2015. PMID: 25957815 Free article.
A Novel Tricyclic Polyketide, Vanitaracin A, Specifically Inhibits the Entry of Hepatitis B and D Viruses by Targeting Sodium Taurocholate Cotransporting Polypeptide.
Kaneko M, Watashi K, Kamisuki S, Matsunaga H, Iwamoto M, Kawai F, Ohashi H, Tsukuda S, Shimura S, Suzuki R, Aizaki H, Sugiyama M, Park SY, Ito T, Ohtani N, Sugawara F, Tanaka Y, Mizokami M, Sureau C, Wakita T. Kaneko M, et al. Among authors: sugiyama m. J Virol. 2015 Dec;89(23):11945-53. doi: 10.1128/JVI.01855-15. Epub 2015 Sep 16. J Virol. 2015. PMID: 26378168 Free PMC article.
2,548 results