Pittman DD - Search Results

1

Hemostatic efficacy of marstacimab alone or in combination with bypassing agents in hemophilia plasmas and a mouse bleeding model.

Pittman DD, Rakhe S, Bowley SR, Jasuja R, Barakat A, Murphy JE. Pittman DD, et al. Res Pract Thromb Haemost. 2022 Mar 16;6(2):e12679. doi: 10.1002/rth2.12679. eCollection 2022 Feb. Res Pract Thromb Haemost. 2022. PMID: 35316941 Free PMC article.

2

Translational Pharmacokinetic/Pharmacodynamic Characterization and Target-Mediated Drug Disposition Modeling of an Anti-Tissue Factor Pathway Inhibitor Antibody, PF-06741086.

Parng C, Singh P, Pittman DD, Wright K, Leary B, Patel-Hett S, Rakhe S, Stejskal J, Peraza M, Dufield D, Murphy JE, Webster R. Parng C, et al. Among authors: pittman dd. J Pharm Sci. 2018 Jul;107(7):1995-2004. doi: 10.1016/j.xphs.2018.03.010. Epub 2018 Mar 20. J Pharm Sci. 2018. PMID: 29571739

3

Marstacimab, a tissue factor pathway inhibitor neutralizing antibody, improves coagulation parameters of ex vivo dosed haemophilic blood and plasmas.

Patel-Hett S, Martin EJ, Mohammed BM, Rakhe S, Sun P, Barrett JC, Nolte ME, Kuhn J, Pittman DD, Murphy JE, Brophy DF. Patel-Hett S, et al. Among authors: pittman dd. Haemophilia. 2019 Sep;25(5):797-806. doi: 10.1111/hae.13820. Epub 2019 Jul 23. Haemophilia. 2019. PMID: 31336410

4

A first-in-human study of the safety, tolerability, pharmacokinetics and pharmacodynamics of PF-06741086, an anti-tissue factor pathway inhibitor mAb, in healthy volunteers.

Cardinal M, Kantaridis C, Zhu T, Sun P, Pittman DD, Murphy JE, Arkin S. Cardinal M, et al. Among authors: pittman dd. J Thromb Haemost. 2018 Sep;16(9):1722-1731. doi: 10.1111/jth.14207. Epub 2018 Jul 20. J Thromb Haemost. 2018. PMID: 29908043 Free article. Clinical Trial.

5

Antibodies against the erythroferrone N-terminal domain prevent hepcidin suppression and ameliorate murine thalassemia.

Arezes J, Foy N, McHugh K, Quinkert D, Benard S, Sawant A, Frost JN, Armitage AE, Pasricha SR, Lim PJ, Tam MS, Lavallie E, Pittman DD, Cunningham O, Lambert M, Murphy JE, Draper SJ, Jasuja R, Drakesmith H. Arezes J, et al. Among authors: pittman dd. Blood. 2020 Feb 20;135(8):547-557. doi: 10.1182/blood.2019003140. Blood. 2020. PMID: 31899794 Free PMC article.

6

Phase 1 dose-escalating study to evaluate the safety, pharmacokinetics, and pharmacodynamics of a recombinant factor Xa variant (FXa^I16L ).

Parsons-Rich D, Hua F, Li G, Kantaridis C, Pittman DD, Arkin S. Parsons-Rich D, et al. Among authors: pittman dd. J Thromb Haemost. 2017 May;15(5):931-937. doi: 10.1111/jth.13673. Epub 2017 Apr 25. J Thromb Haemost. 2017. PMID: 28294526 Free article. Clinical Trial.

7

Investigating the clearance of VWF A-domains using site-directed PEGylation and novel N-linked glycosylation.

Fazavana J, Brophy TM, Chion A, Cooke N, Terraube V, Cohen J, Parng C, Pittman D, Cunningham O, Lambert M, O'Donnell JS, O'Sullivan JM. Fazavana J, et al. J Thromb Haemost. 2020 Jun;18(6):1278-1290. doi: 10.1111/jth.14785. Epub 2020 Mar 30. J Thromb Haemost. 2020. PMID: 32108991 Free PMC article.

8

To Clot or Not to Clot: Deepening Our Understanding of Alterations in the Hemostatic System.

Reagan WJ, Brooks MB, Grozovsky R, Pittman D, Vitsky A, Brenneman K. Reagan WJ, et al. Toxicol Pathol. 2022 Oct;50(7):890-894. doi: 10.1177/01926233221125172. Epub 2022 Sep 17. Toxicol Pathol. 2022. PMID: 36117463 Review.

9

Using a Systems Pharmacology Model of the Blood Coagulation Network to Predict the Effects of Various Therapies on Biomarkers.

Nayak S, Lee D, Patel-Hett S, Pittman DD, Martin SW, Heatherington AC, Vicini P, Hua F. Nayak S, et al. Among authors: pittman dd. CPT Pharmacometrics Syst Pharmacol. 2015 Jul;4(7):396-405. doi: 10.1002/psp4.50. Epub 2015 Jun 19. CPT Pharmacometrics Syst Pharmacol. 2015. PMID: 26312163 Free PMC article.

10

Structure-function relationships of factor VIII elucidated through recombinant DNA technology.

Pittman DD, Kaufman RJ. Pittman DD, et al. Thromb Haemost. 1989 Apr 25;61(2):161-5. Thromb Haemost. 1989. PMID: 2501893 Review. No abstract available.

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