Lee SY - Search Results

1

Structure and Mechanism of the Lipid Flippase MurJ.

Kuk ACY, Hao A, Lee SY. Kuk ACY, et al. Among authors: lee sy. Annu Rev Biochem. 2022 Jun 21;91:705-729. doi: 10.1146/annurev-biochem-040320-105145. Epub 2022 Mar 23. Annu Rev Biochem. 2022. PMID: 35320686 Free PMC article. Review.

2

Crystal structure of the MOP flippase MurJ in an inward-facing conformation.

Kuk AC, Mashalidis EH, Lee SY. Kuk AC, et al. Among authors: lee sy. Nat Struct Mol Biol. 2017 Feb;24(2):171-176. doi: 10.1038/nsmb.3346. Epub 2016 Dec 26. Nat Struct Mol Biol. 2017. PMID: 28024149 Free PMC article.

3

GlcNAc-1-P-transferase-tunicamycin complex structure reveals basis for inhibition of N-glycosylation.

Yoo J, Mashalidis EH, Kuk ACY, Yamamoto K, Kaeser B, Ichikawa S, Lee SY. Yoo J, et al. Among authors: lee sy. Nat Struct Mol Biol. 2018 Mar;25(3):217-224. doi: 10.1038/s41594-018-0031-y. Epub 2018 Feb 19. Nat Struct Mol Biol. 2018. PMID: 29459785 Free PMC article.

4

Visualizing conformation transitions of the Lipid II flippase MurJ.

Kuk ACY, Hao A, Guan Z, Lee SY. Kuk ACY, et al. Among authors: lee sy. Nat Commun. 2019 Apr 15;10(1):1736. doi: 10.1038/s41467-019-09658-0. Nat Commun. 2019. PMID: 30988294 Free PMC article.

5

Synthesis and evaluation of cyclopentane-based muraymycin analogs targeting MraY.

Kwak SH, Lim WY, Hao A, Mashalidis EH, Kwon DY, Jeong P, Kim MJ, Lee SY, Hong J. Kwak SH, et al. Among authors: lee sy. Eur J Med Chem. 2021 Apr 5;215:113272. doi: 10.1016/j.ejmech.2021.113272. Epub 2021 Feb 6. Eur J Med Chem. 2021. PMID: 33607457 Free PMC article.

6

Structural insights into the FtsEX-EnvC complex regulation on septal peptidoglycan hydrolysis in Vibrio cholerae.

Hao A, Suo Y, Lee SY. Hao A, et al. Among authors: lee sy. Structure. 2024 Feb 1;32(2):188-199.e5. doi: 10.1016/j.str.2023.11.007. Epub 2023 Dec 8. Structure. 2024. PMID: 38070498

7

Development of a natural product optimization strategy for inhibitors against MraY, a promising antibacterial target.

Yamamoto K, Sato T, Hao A, Asao K, Kaguchi R, Kusaka S, Ruddarraju RR, Kazamori D, Seo K, Takahashi S, Horiuchi M, Yokota SI, Lee SY, Ichikawa S. Yamamoto K, et al. Among authors: lee sy. Nat Commun. 2024 Jun 14;15(1):5085. doi: 10.1038/s41467-024-49484-7. Nat Commun. 2024. PMID: 38877016 Free PMC article.

8

Crystal structure of MraY, an essential membrane enzyme for bacterial cell wall synthesis.

Chung BC, Zhao J, Gillespie RA, Kwon DY, Guan Z, Hong J, Zhou P, Lee SY. Chung BC, et al. Among authors: lee sy. Science. 2013 Aug 30;341(6149):1012-1016. doi: 10.1126/science.1236501. Science. 2013. PMID: 23990562 Free PMC article.

9

Structural insights into inhibition of lipid I production in bacterial cell wall synthesis.

Chung BC, Mashalidis EH, Tanino T, Kim M, Matsuda A, Hong J, Ichikawa S, Lee SY. Chung BC, et al. Among authors: lee sy. Nature. 2016 May 26;533(7604):557-560. doi: 10.1038/nature17636. Epub 2016 Apr 18. Nature. 2016. PMID: 27088606 Free PMC article.

10

Chemical logic of MraY inhibition by antibacterial nucleoside natural products.

Mashalidis EH, Kaeser B, Terasawa Y, Katsuyama A, Kwon DY, Lee K, Hong J, Ichikawa S, Lee SY. Mashalidis EH, et al. Among authors: lee sy, lee k. Nat Commun. 2019 Jul 2;10(1):2917. doi: 10.1038/s41467-019-10957-9. Nat Commun. 2019. PMID: 31266949 Free PMC article.

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