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Epigenetic landscape in the kick-and-kill therapeutic vaccine BCN02 clinical trial is associated with antiretroviral treatment interruption (ATI) outcome.
Oriol-Tordera B, Esteve-Codina A, Berdasco M, Rosás-Umbert M, Gonçalves E, Duran-Castells C, Català-Moll F, Llano A, Cedeño S, Puertas MC, Tolstrup M, Søgaard OS, Clotet B, Martínez-Picado J, Hanke T, Combadiere B, Paredes R, Hartigan-O'Connor D, Esteller M, Meulbroek M, Calle ML, Sanchez-Pla A, Moltó J, Mothe B, Brander C, Ruiz-Riol M. Oriol-Tordera B, et al. EBioMedicine. 2022 Apr;78:103956. doi: 10.1016/j.ebiom.2022.103956. Epub 2022 Mar 21. EBioMedicine. 2022. PMID: 35325780 Free PMC article.
Inflammatory macrophages reprogram to immunosuppression by reducing mitochondrial translation.
Cortés M, Brischetto A, Martinez-Campanario MC, Ninfali C, Domínguez V, Fernández S, Celis R, Esteve-Codina A, Lozano JJ, Sidorova J, Garrabou G, Siegert AM, Enrich C, Pintado B, Morales-Ruiz M, Castro P, Cañete JD, Postigo A. Cortés M, et al. Nat Commun. 2023 Nov 17;14(1):7471. doi: 10.1038/s41467-023-42277-4. Nat Commun. 2023. PMID: 37978290 Free PMC article.
The EMT factor ZEB1 paradoxically inhibits EMT in BRAF-mutant carcinomas.
Sánchez-Tilló E, Pedrosa L, Vila I, Chen Y, Győrffy B, Sánchez-Moral L, Siles L, Lozano JJ, Esteve-Codina A, Darling DS, Cuatrecasas M, Castells A, Maurel J, Postigo A. Sánchez-Tilló E, et al. JCI Insight. 2023 Oct 23;8(20):e164629. doi: 10.1172/jci.insight.164629. JCI Insight. 2023. PMID: 37870961 Free PMC article.
A human in vitro neuronal model for studying homeostatic plasticity at the network level.
Yuan X, Puvogel S, van Rhijn JR, Ciptasari U, Esteve-Codina A, Meijer M, Rouschop S, van Hugte EJH, Oudakker A, Schoenmaker C, Frega M, Schubert D, Franke B, Nadif Kasri N. Yuan X, et al. Stem Cell Reports. 2023 Nov 14;18(11):2222-2239. doi: 10.1016/j.stemcr.2023.09.011. Epub 2023 Oct 19. Stem Cell Reports. 2023. PMID: 37863044 Free PMC article.
Atherosclerotic plaque development in mice is enhanced by myeloid ZEB1 downregulation.
Martinez-Campanario MC, Cortés M, Moreno-Lanceta A, Han L, Ninfali C, Domínguez V, Andrés-Manzano MJ, Farràs M, Esteve-Codina A, Enrich C, Díaz-Crespo FJ, Pintado B, Escolà-Gil JC, García de Frutos P, Andrés V, Melgar-Lesmes P, Postigo A. Martinez-Campanario MC, et al. Nat Commun. 2023 Dec 14;14(1):8316. doi: 10.1038/s41467-023-43896-7. Nat Commun. 2023. PMID: 38097578 Free PMC article.
CPT1A in AgRP neurons is required for sex-dependent regulation of feeding and thirst.
Zagmutt S, Mera P, González-García I, Ibeas K, Romero MDM, Obri A, Martin B, Esteve-Codina A, Soler-Vázquez MC, Bastias-Pérez M, Cañes L, Augé E, Pelegri C, Vilaplana J, Ariza X, García J, Martinez-González J, Casals N, López M, Palmiter R, Sanz E, Quintana A, Herrero L, Serra D. Zagmutt S, et al. Biol Sex Differ. 2023 Mar 25;14(1):14. doi: 10.1186/s13293-023-00498-8. Biol Sex Differ. 2023. PMID: 36966335 Free PMC article.
107 results