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Page 1
Reduced expression of mitochondrial complex I subunit Ndufs2 does not impact healthspan in mice.
McElroy GS, Chakrabarty RP, D'Alessandro KB, Hu YS, Vasan K, Tan J, Stoolman JS, Weinberg SE, Steinert EM, Reyfman PA, Singer BD, Ladiges WC, Gao L, Lopéz-Barneo J, Ridge K, Budinger GRS, Chandel NS. McElroy GS, et al. Among authors: ridge k. Sci Rep. 2022 Mar 25;12(1):5196. doi: 10.1038/s41598-022-09074-3. Sci Rep. 2022. PMID: 35338200 Free PMC article.
Proapoptotic Bid is required for pulmonary fibrosis.
Budinger GR, Mutlu GM, Eisenbart J, Fuller AC, Bellmeyer AA, Baker CM, Wilson M, Ridge K, Barrett TA, Lee VY, Chandel NS. Budinger GR, et al. Among authors: ridge k. Proc Natl Acad Sci U S A. 2006 Mar 21;103(12):4604-9. doi: 10.1073/pnas.0507604103. Epub 2006 Mar 14. Proc Natl Acad Sci U S A. 2006. PMID: 16537427 Free PMC article.
Mitochondrial complex III-generated oxidants activate ASK1 and JNK to induce alveolar epithelial cell death following exposure to particulate matter air pollution.
Soberanes S, Urich D, Baker CM, Burgess Z, Chiarella SE, Bell EL, Ghio AJ, De Vizcaya-Ruiz A, Liu J, Ridge KM, Kamp DW, Chandel NS, Schumacker PT, Mutlu GM, Budinger GR. Soberanes S, et al. J Biol Chem. 2009 Jan 23;284(4):2176-86. doi: 10.1074/jbc.M808844200. Epub 2008 Nov 25. J Biol Chem. 2009. PMID: 19033436 Free PMC article.
Mitochondrial reactive oxygen species are required for hypoxia-induced degradation of keratin intermediate filaments.
Na N, Chandel NS, Litvan J, Ridge KM. Na N, et al. FASEB J. 2010 Mar;24(3):799-809. doi: 10.1096/fj.08-128967. Epub 2009 Nov 6. FASEB J. 2010. PMID: 19897662 Free PMC article.
Accordingly, we provide evidence that hypoxia promotes the disassembly and degradation of the keratin IF network via mitochondrial complex III-generated reactive oxygen species.-Na, N., Chandel, N. S., Litvan, J., Ridge, K. M. Mitochondrial reactive oxygen species a …
Accordingly, we provide evidence that hypoxia promotes the disassembly and degradation of the keratin IF network via mitochondrial complex I …
Suppression of inflammation and acute lung injury by Miz1 via repression of C/EBP-δ.
Do-Umehara HC, Chen C, Urich D, Zhou L, Qiu J, Jang S, Zander A, Baker MA, Eilers M, Sporn PH, Ridge KM, Sznajder JI, Budinger GR, Mutlu GM, Lin A, Liu J. Do-Umehara HC, et al. Nat Immunol. 2013 May;14(5):461-9. doi: 10.1038/ni.2566. Epub 2013 Mar 24. Nat Immunol. 2013. Retraction in: Nat Immunol. 2025 Jan 7. doi: 10.1038/s41590-024-02070-x PMID: 23525087 Free PMC article. Retracted.
202 results