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Stimulation of Gs signaling in MC4R cells by DREADD increases energy expenditure, suppresses food intake, and increases locomotor activity in mice.
Matsumura S, Miyakita M, Miyamori H, Kyo S, Shima D, Yokokawa T, Ishikawa F, Sasaki T, Jinno T, Tanaka J, Goto T, Momma K, Ishihara K, Berdeaux R, Inoue K. Matsumura S, et al. Among authors: inoue k. Am J Physiol Endocrinol Metab. 2022 May 1;322(5):E436-E445. doi: 10.1152/ajpendo.00439.2021. Epub 2022 Mar 28. Am J Physiol Endocrinol Metab. 2022. PMID: 35344393 Free article.
Transforming growth factor-beta in the brain is activated by exercise and increases mobilization of fat-related energy substrates in rats.
Shibakusa T, Mizunoya W, Okabe Y, Matsumura S, Iwaki Y, Okuno A, Shibata K, Inoue K, Fushiki T. Shibakusa T, et al. Among authors: inoue k. Am J Physiol Regul Integr Comp Physiol. 2007 May;292(5):R1851-61. doi: 10.1152/ajpregu.00632.2006. Epub 2007 Feb 15. Am J Physiol Regul Integr Comp Physiol. 2007. PMID: 17303681 Free article.
Intracisternal administration of transforming growth factor-beta evokes fever through the induction of cyclooxygenase-2 in brain endothelial cells.
Matsumura S, Shibakusa T, Fujikawa T, Yamada H, Matsumura K, Inoue K, Fushiki T. Matsumura S, et al. Among authors: inoue k. Am J Physiol Regul Integr Comp Physiol. 2008 Jan;294(1):R266-75. doi: 10.1152/ajpregu.00181.2007. Epub 2007 Oct 24. Am J Physiol Regul Integr Comp Physiol. 2008. PMID: 17959708 Free article.
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