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Inhibiting a dynamic viral protease by targeting a non-catalytic cysteine.
Hulce KR, Jaishankar P, Lee GM, Bohn MF, Connelly EJ, Wucherer K, Ongpipattanakul C, Volk RF, Chuo SW, Arkin MR, Renslo AR, Craik CS. Hulce KR, et al. Cell Chem Biol. 2022 May 19;29(5):785-798.e19. doi: 10.1016/j.chembiol.2022.03.007. Epub 2022 Mar 31. Cell Chem Biol. 2022. PMID: 35364007 Free PMC article.
Determination of ubiquitin fitness landscapes under different chemical stresses in a classroom setting.
Mavor D, Barlow K, Thompson S, Barad BA, Bonny AR, Cario CL, Gaskins G, Liu Z, Deming L, Axen SD, Caceres E, Chen W, Cuesta A, Gate RE, Green EM, Hulce KR, Ji W, Kenner LR, Mensa B, Morinishi LS, Moss SM, Mravic M, Muir RK, Niekamp S, Nnadi CI, Palovcak E, Poss EM, Ross TD, Salcedo EC, See SK, Subramaniam M, Wong AW, Li J, Thorn KS, Conchúir SÓ, Roscoe BP, Chow ED, DeRisi JL, Kortemme T, Bolon DN, Fraser JS. Mavor D, et al. Among authors: hulce kr. Elife. 2016 Apr 25;5:e15802. doi: 10.7554/eLife.15802. Elife. 2016. PMID: 27111525 Free PMC article.