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Page 1
USP28 enables oncogenic transformation of respiratory cells, and its inhibition potentiates molecular therapy targeting mutant EGFR, BRAF and PI3K.
Prieto-Garcia C, Hartmann O, Reissland M, Braun F, Bozkurt S, Pahor N, Fuss C, Schirbel A, Schülein-Völk C, Buchberger A, Calzado Canale MA, Rosenfeldt M, Dikic I, Münch C, Diefenbacher ME. Prieto-Garcia C, et al. Among authors: dikic i. Mol Oncol. 2022 Sep;16(17):3082-3106. doi: 10.1002/1878-0261.13217. Epub 2022 Apr 30. Mol Oncol. 2022. PMID: 35364627 Free PMC article.
Hitchhiking on selective autophagy.
Münch C, Dikic I. Münch C, et al. Among authors: dikic i. Nat Cell Biol. 2018 Feb;20(2):122-124. doi: 10.1038/s41556-018-0036-0. Nat Cell Biol. 2018. PMID: 29371706 No abstract available.
Loss of the selective autophagy receptor p62 impairs murine myeloid leukemia progression and mitophagy.
Nguyen TD, Shaid S, Vakhrusheva O, Koschade SE, Klann K, Thölken M, Baker F, Zhang J, Oellerich T, Sürün D, Derlet A, Haberbosch I, Eimer S, Osiewacz HD, Behrends C, Münch C, Dikic I, Brandts CH. Nguyen TD, et al. Among authors: dikic i. Blood. 2019 Jan 10;133(2):168-179. doi: 10.1182/blood-2018-02-833475. Epub 2018 Nov 29. Blood. 2019. PMID: 30498063 Free article.
SIK2 orchestrates actin-dependent host response upon Salmonella infection.
Hahn M, Covarrubias-Pinto A, Herhaus L, Satpathy S, Klann K, Boyle KB, Münch C, Rajalingam K, Randow F, Choudhary C, Dikic I. Hahn M, et al. Among authors: dikic i. Proc Natl Acad Sci U S A. 2021 May 11;118(19):e2024144118. doi: 10.1073/pnas.2024144118. Proc Natl Acad Sci U S A. 2021. PMID: 33947818 Free PMC article.
Minimized combinatorial CRISPR screens identify genetic interactions in autophagy.
Diehl V, Wegner M, Grumati P, Husnjak K, Schaubeck S, Gubas A, Shah VJ, Polat IH, Langschied F, Prieto-Garcia C, Müller K, Kalousi A, Ebersberger I, Brandts CH, Dikic I, Kaulich M. Diehl V, et al. Among authors: dikic i. Nucleic Acids Res. 2021 Jun 4;49(10):5684-5704. doi: 10.1093/nar/gkab309. Nucleic Acids Res. 2021. PMID: 33956155 Free PMC article.
Inhibition of USP28 overcomes Cisplatin-resistance of squamous tumors by suppression of the Fanconi anemia pathway.
Prieto-Garcia C, Hartmann O, Reissland M, Fischer T, Maier CR, Rosenfeldt M, Schülein-Völk C, Klann K, Kalb R, Dikic I, Münch C, Diefenbacher ME. Prieto-Garcia C, et al. Among authors: dikic i. Cell Death Differ. 2022 Mar;29(3):568-584. doi: 10.1038/s41418-021-00875-z. Epub 2021 Oct 5. Cell Death Differ. 2022. PMID: 34611298 Free PMC article.
369 results