Leenay RT - Search Results

1

A functional map of HIV-host interactions in primary human T cells.

Hiatt J, Hultquist JF, McGregor MJ, Bouhaddou M, Leenay RT, Simons LM, Young JM, Haas P, Roth TL, Tobin V, Wojcechowskyj JA, Woo JM, Rathore U, Cavero DA, Shifrut E, Nguyen TT, Haas KM, Malik HS, Doudna JA, May AP, Marson A, Krogan NJ. Hiatt J, et al. Among authors: leenay rt. Nat Commun. 2022 Apr 1;13(1):1752. doi: 10.1038/s41467-022-29346-w. Nat Commun. 2022. PMID: 35365639 Free PMC article.

2

Large dataset enables prediction of repair after CRISPR-Cas9 editing in primary T cells.

Leenay RT, Aghazadeh A, Hiatt J, Tse D, Roth TL, Apathy R, Shifrut E, Hultquist JF, Krogan N, Wu Z, Cirolia G, Canaj H, Leonetti MD, Marson A, May AP, Zou J. Leenay RT, et al. Nat Biotechnol. 2019 Sep;37(9):1034-1037. doi: 10.1038/s41587-019-0203-2. Epub 2019 Jul 29. Nat Biotechnol. 2019. PMID: 31359007 Free PMC article.

3

Fast-Seq: A Simple Method for Rapid and Inexpensive Validation of Packaged Single-Stranded Adeno-Associated Viral Genomes in Academic Settings.

Maynard LH, Smith O, Tilmans NP, Tham E, Hosseinzadeh S, Tan W, Leenay R, May AP, Paulk NK. Maynard LH, et al. Hum Gene Ther Methods. 2019 Dec;30(6):195-205. doi: 10.1089/hgtb.2019.110. Hum Gene Ther Methods. 2019. PMID: 31855083 Free PMC article.

4

Modular one-pot assembly of CRISPR arrays enables library generation and reveals factors influencing crRNA biogenesis.

Liao C, Ttofali F, Slotkowski RA, Denny SR, Cecil TD, Leenay RT, Keung AJ, Beisel CL. Liao C, et al. Among authors: leenay rt. Nat Commun. 2019 Jul 3;10(1):2948. doi: 10.1038/s41467-019-10747-3. Nat Commun. 2019. PMID: 31270316 Free PMC article.

5

Genome Editing with CRISPR-Cas9 in Lactobacillus plantarum Revealed That Editing Outcomes Can Vary Across Strains and Between Methods.

Leenay RT, Vento JM, Shah M, Martino ME, Leulier F, Beisel CL. Leenay RT, et al. Biotechnol J. 2019 Mar;14(3):e1700583. doi: 10.1002/biot.201700583. Epub 2018 Sep 20. Biotechnol J. 2019. PMID: 30156038

6

Current and future prospects for CRISPR-based tools in bacteria.

Luo ML, Leenay RT, Beisel CL. Luo ML, et al. Among authors: leenay rt. Biotechnol Bioeng. 2016 May;113(5):930-43. doi: 10.1002/bit.25851. Epub 2015 Oct 27. Biotechnol Bioeng. 2016. PMID: 26460902 Free PMC article. Review.

7

CRISPR RNA-Dependent Binding and Cleavage of Endogenous RNAs by the Campylobacter jejuni Cas9.

Dugar G, Leenay RT, Eisenbart SK, Bischler T, Aul BU, Beisel CL, Sharma CM. Dugar G, et al. Among authors: leenay rt. Mol Cell. 2018 Mar 1;69(5):893-905.e7. doi: 10.1016/j.molcel.2018.01.032. Mol Cell. 2018. PMID: 29499139 Free PMC article.

8

Deciphering, Communicating, and Engineering the CRISPR PAM.

Leenay RT, Beisel CL. Leenay RT, et al. J Mol Biol. 2017 Jan 20;429(2):177-191. doi: 10.1016/j.jmb.2016.11.024. Epub 2016 Dec 1. J Mol Biol. 2017. PMID: 27916599 Free PMC article. Review.

9

Repurposing endogenous type I CRISPR-Cas systems for programmable gene repression.

Luo ML, Mullis AS, Leenay RT, Beisel CL. Luo ML, et al. Among authors: leenay rt. Nucleic Acids Res. 2015 Jan;43(1):674-81. doi: 10.1093/nar/gku971. Epub 2014 Oct 17. Nucleic Acids Res. 2015. PMID: 25326321 Free PMC article.

10

Identifying and Visualizing Functional PAM Diversity across CRISPR-Cas Systems.

Leenay RT, Maksimchuk KR, Slotkowski RA, Agrawal RN, Gomaa AA, Briner AE, Barrangou R, Beisel CL. Leenay RT, et al. Mol Cell. 2016 Apr 7;62(1):137-47. doi: 10.1016/j.molcel.2016.02.031. Epub 2016 Mar 31. Mol Cell. 2016. PMID: 27041224 Free PMC article.

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