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A whole genome sequencing study of moderate to severe asthma identifies a lung function locus associated with asthma risk.
Chang D, Hunkapiller J, Bhangale T, Reeder J, Mukhyala K, Tom J, Cowgill A, Vogel J, Forrest WF, Khan Z, Stockwell A, McCarthy MI, Staton TL, Olsson J, Holweg CTJ, Cheung DS, Chen H, Brauer MJ, Graham RR, Behrens T, Wilson MS, Arron JR, Choy DF, Yaspan BL. Chang D, et al. Among authors: cheung ds. Sci Rep. 2022 Apr 2;12(1):5574. doi: 10.1038/s41598-022-09447-8. Sci Rep. 2022. PMID: 35368043 Free PMC article.
Astegolimab (anti-ST2) efficacy and safety in adults with severe asthma: A randomized clinical trial.
Kelsen SG, Agache IO, Soong W, Israel E, Chupp GL, Cheung DS, Theess W, Yang X, Staton TL, Choy DF, Fong A, Dash A, Dolton M, Pappu R, Brightling CE. Kelsen SG, et al. Among authors: cheung ds. J Allergy Clin Immunol. 2021 Sep;148(3):790-798. doi: 10.1016/j.jaci.2021.03.044. Epub 2021 Apr 16. J Allergy Clin Immunol. 2021. PMID: 33872652 Free article. Clinical Trial.
Population repeated time-to-event analysis of exacerbations in asthma patients: A novel approach for predicting asthma exacerbations based on biomarkers, spirometry, and diaries/questionnaires.
Svensson RJ, Ribbing J, Kotani N, Dolton M, Vadhavkar S, Cheung D, Staton T, Choy DF, Putnam W, Jin J, Budha N, Karlsson MO, Quartino A, Zhu R. Svensson RJ, et al. CPT Pharmacometrics Syst Pharmacol. 2021 Oct;10(10):1221-1235. doi: 10.1002/psp4.12690. Epub 2021 Aug 5. CPT Pharmacometrics Syst Pharmacol. 2021. PMID: 34346168 Free PMC article. Clinical Trial.
Astegolimab, an anti-ST2, in chronic obstructive pulmonary disease (COPD-ST2OP): a phase 2a, placebo-controlled trial.
Yousuf AJ, Mohammed S, Carr L, Yavari Ramsheh M, Micieli C, Mistry V, Haldar K, Wright A, Novotny P, Parker S, Glover S, Finch J, Quann N, Brookes CL, Hobson R, Ibrahim W, Russell RJ, John C, Grimbaldeston MA, Choy DF, Cheung D, Steiner M, Greening NJ, Brightling CE. Yousuf AJ, et al. Lancet Respir Med. 2022 May;10(5):469-477. doi: 10.1016/S2213-2600(21)00556-7. Epub 2022 Mar 24. Lancet Respir Med. 2022. PMID: 35339234 Clinical Trial.
A survivor: the eosinophil as a regulator in asthma.
Cheung DS, Grayson MH. Cheung DS, et al. J Allergy Clin Immunol. 2015 Feb;135(2):461-2. doi: 10.1016/j.jaci.2014.10.054. Epub 2014 Dec 19. J Allergy Clin Immunol. 2015. PMID: 25533648 No abstract available.
Cysteinyl leukotriene receptor 1 expression identifies a subset of neutrophils during the antiviral response that contributes to postviral atopic airway disease.
Cheung DS, Sigua JA, Simpson PM, Yan K, Hussain SA, Santoro JL, Buell EJ, Hunter DA, Rohlfing M, Patadia D, Grayson MH. Cheung DS, et al. J Allergy Clin Immunol. 2018 Oct;142(4):1206-1217.e5. doi: 10.1016/j.jaci.2017.11.026. Epub 2017 Dec 18. J Allergy Clin Immunol. 2018. PMID: 29269317 Free PMC article.
184 results