Cho S - Search Results

1

Elucidating the structure and cytochrome P450-mediated mechanism for novel metabolites of GDC-0575 in rats.

Zhang C, Cho S, Napolitano JG, Russell D, Gu C, Deese A, Han C, Chen Y, Ma S. Zhang C, et al. Among authors: cho s. Xenobiotica. 2022 Mar;52(3):219-228. doi: 10.1080/00498254.2022.2062685. Epub 2022 Apr 21. Xenobiotica. 2022. PMID: 35379057

2

Absorption, metabolism and excretion of pictilisib, a potent pan-class I phosphatidylinositol-3-Kinase (PI3K) inhibitor, in rats, dogs, and humans.

Yue Q, Khojasteh SC, Cho S, Ma S, Mulder T, Chen J, Pang J, Ding X, Deese A, Pellet JD, Siebers N, Joas L, Salphati L, Ware JA. Yue Q, et al. Among authors: cho s. Xenobiotica. 2021 Jul;51(7):796-810. doi: 10.1080/00498254.2021.1923859. Epub 2021 May 24. Xenobiotica. 2021. PMID: 33938357

3

Absorption, Metabolism, and Excretion of Taselisib (GDC-0032), a Potent β-Sparing PI3K Inhibitor in Rats, Dogs, and Humans.

Ma S, Cho S, Sahasranaman S, Zhao W, Pang J, Ding X, Dean B, Wang B, Hsu JY, Ware J, Salphati L. Ma S, et al. Among authors: cho s. Drug Metab Dispos. 2023 Apr;51(4):436-450. doi: 10.1124/dmd.122.001096. Epub 2023 Jan 9. Drug Metab Dispos. 2023. PMID: 36623882

4

The Absolute Bioavailability and Absorption, Metabolism, and Excretion of Ipatasertib, a Potent and Highly Selective Protein Kinase B (Akt) Inhibitor.

Takahashi RH, Malhi V, Liederer BM, Cho S, Deng Y, Dean B, Nugteren J, Yost E, Al-Sayah MA, Sane R, Kshirsagar S, Ma S, Musib L. Takahashi RH, et al. Among authors: cho s. Drug Metab Dispos. 2023 Oct;51(10):1332-1341. doi: 10.1124/dmd.122.001175. Epub 2023 Jul 31. Drug Metab Dispos. 2023. PMID: 37524543

5

Mass Balance, Metabolic Pathways, Absolute Bioavailability, and Pharmacokinetics of Giredestrant in Healthy Subjects.

Kshirsagar S, Chen YC, Yu J, Gates MR, Kawakatsu S, Khojasteh SC, Ma S, Musib L, Malhi V, Osaghae U, Wang J, Cho S, Tang YT, Zhang D, Zhao W, De Bruyn T. Kshirsagar S, et al. Among authors: cho s. Drug Metab Dispos. 2024 Jul 16;52(8):847-857. doi: 10.1124/dmd.124.001688. Drug Metab Dispos. 2024. PMID: 38834357

6

Bioactivation and reactivity research advances - 2021 year in review.

Jackson KD, Argikar UA, Cho S, Crouch RD, Driscoll JP, Heck CJS, King L, Maw HH, Miller GP, Seneviratne HK, Wang S, Wei C, Zhang D, Khojasteh SC. Jackson KD, et al. Among authors: cho s. Drug Metab Rev. 2022 Aug;54(3):246-281. doi: 10.1080/03602532.2022.2097254. Epub 2022 Aug 5. Drug Metab Rev. 2022. PMID: 35876116 Free PMC article. Review.

7

Discovery of Unprecedented Human Stercobilin Conjugates.

Cho S, Cheruzel L, Cai J, Wrigley SK, Gemmell RT, Kokubun T, Steele JCP, Salphati L, Zhang D, Khojasteh SC. Cho S, et al. Drug Metab Dispos. 2024 Aug 14;52(9):981-987. doi: 10.1124/dmd.124.001725. Drug Metab Dispos. 2024. PMID: 38991780

8

Biotransformation novel advances - 2021 year in review.

Khojasteh SC, Argikar UA, Cho S, Crouch R, Heck CJS, Johnson KM, Kalgutkar AS, King L, Maw HH, Seneviratne HK, Wang S, Wei C, Zhang D, Jackson KD. Khojasteh SC, et al. Among authors: cho s. Drug Metab Rev. 2022 Aug;54(3):207-245. doi: 10.1080/03602532.2022.2097253. Epub 2022 Aug 30. Drug Metab Rev. 2022. PMID: 35815654 Free PMC article. Review.

9

Dissecting the human gut microbiome to better decipher drug liability: A once-forgotten organ takes center stage.

Cai J, Auster A, Cho S, Lai Z. Cai J, et al. Among authors: cho s. J Adv Res. 2023 Oct;52:171-201. doi: 10.1016/j.jare.2023.07.002. Epub 2023 Jul 5. J Adv Res. 2023. PMID: 37419381 Free PMC article.

10

Bioactivation and reactivity research advances - 2022 year in review‡.

Wang S, Argikar UA, Cheruzel L, Cho S, Crouch RD, Dhaware D, Heck CJS, Johnson KM, Kalgutkar AS, King L, Liu J, Ma B, Maw H, Miller GP, Seneviratne HK, Takahashi RH, Wei C, Khojasteh SC. Wang S, et al. Among authors: cho s. Drug Metab Rev. 2023 Nov;55(4):267-300. doi: 10.1080/03602532.2023.2244193. Epub 2023 Aug 22. Drug Metab Rev. 2023. PMID: 37608698 Review.

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