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Page 1
Structural definition of a pan-sarbecovirus neutralizing epitope on the spike S2 subunit.
Hurlburt NK, Homad LJ, Sinha I, Jennewein MF, MacCamy AJ, Wan YH, Boonyaratanakornkit J, Sholukh AM, Jackson AM, Zhou P, Burton DR, Andrabi R, Ozorowski G, Ward AB, Stamatatos L, Pancera M, McGuire AT. Hurlburt NK, et al. Among authors: homad lj. Commun Biol. 2022 Apr 11;5(1):342. doi: 10.1038/s42003-022-03262-7. Commun Biol. 2022. PMID: 35411021 Free PMC article.
Analysis of a SARS-CoV-2-Infected Individual Reveals Development of Potent Neutralizing Antibodies with Limited Somatic Mutation.
Seydoux E, Homad LJ, MacCamy AJ, Parks KR, Hurlburt NK, Jennewein MF, Akins NR, Stuart AB, Wan YH, Feng J, Whaley RE, Singh S, Boeckh M, Cohen KW, McElrath MJ, Englund JA, Chu HY, Pancera M, McGuire AT, Stamatatos L. Seydoux E, et al. Among authors: homad lj. Immunity. 2020 Jul 14;53(1):98-105.e5. doi: 10.1016/j.immuni.2020.06.001. Epub 2020 Jun 8. Immunity. 2020. PMID: 32561270 Free PMC article.
Isolation and characterization of cross-neutralizing coronavirus antibodies from COVID-19+ subjects.
Jennewein MF, MacCamy AJ, Akins NR, Feng J, Homad LJ, Hurlburt NK, Seydoux E, Wan YH, Stuart AB, Edara VV, Floyd K, Vanderheiden A, Mascola JR, Doria-Rose N, Wang L, Yang ES, Chu HY, Torres JL, Ozorowski G, Ward AB, Whaley RE, Cohen KW, Pancera M, McElrath MJ, Englund JA, Finzi A, Suthar MS, McGuire AT, Stamatatos L. Jennewein MF, et al. Among authors: homad lj. Cell Rep. 2021 Jul 13;36(2):109353. doi: 10.1016/j.celrep.2021.109353. Epub 2021 Jun 22. Cell Rep. 2021. PMID: 34237283 Free PMC article.
Structural basis for broad coronavirus neutralization.
Sauer MM, Tortorici MA, Park YJ, Walls AC, Homad L, Acton OJ, Bowen JE, Wang C, Xiong X, de van der Schueren W, Quispe J, Hoffstrom BG, Bosch BJ, McGuire AT, Veesler D. Sauer MM, et al. Nat Struct Mol Biol. 2021 Jun;28(6):478-486. doi: 10.1038/s41594-021-00596-4. Epub 2021 May 12. Nat Struct Mol Biol. 2021. PMID: 33981021
Characterization of neutralizing antibodies from a SARS-CoV-2 infected individual.
Seydoux E, Homad LJ, MacCamy AJ, Parks KR, Hurlburt NK, Jennewein MF, Akins NR, Stuart AB, Wan YH, Feng J, Nelson RE, Singh S, Cohen KW, McElrath MJ, Englund JA, Chu HY, Pancera M, McGuire AT, Stamatatos L. Seydoux E, et al. Among authors: homad lj. bioRxiv [Preprint]. 2020 May 12:2020.05.12.091298. doi: 10.1101/2020.05.12.091298. bioRxiv. 2020. Update in: Immunity. 2020 Jul 14;53(1):98-105.e5. doi: 10.1016/j.immuni.2020.06.001 PMID: 32511342 Free PMC article. Updated. Preprint.
mRNA vaccination boosts cross-variant neutralizing antibodies elicited by SARS-CoV-2 infection.
Stamatatos L, Czartoski J, Wan YH, Homad LJ, Rubin V, Glantz H, Neradilek M, Seydoux E, Jennewein MF, MacCamy AJ, Feng J, Mize G, De Rosa SC, Finzi A, Lemos MP, Cohen KW, Moodie Z, McElrath MJ, McGuire AT. Stamatatos L, et al. Among authors: homad lj. Science. 2021 Mar 25;372(6549):1413-8. doi: 10.1126/science.abg9175. Online ahead of print. Science. 2021. PMID: 33766944 Free PMC article.
Designed proteins assemble antibodies into modular nanocages.
Divine R, Dang HV, Ueda G, Fallas JA, Vulovic I, Sheffler W, Saini S, Zhao YT, Raj IX, Morawski PA, Jennewein MF, Homad LJ, Wan YH, Tooley MR, Seeger F, Etemadi A, Fahning ML, Lazarovits J, Roederer A, Walls AC, Stewart L, Mazloomi M, King NP, Campbell DJ, McGuire AT, Stamatatos L, Ruohola-Baker H, Mathieu J, Veesler D, Baker D. Divine R, et al. Among authors: homad lj. Science. 2021 Apr 2;372(6537):eabd9994. doi: 10.1126/science.abd9994. Science. 2021. PMID: 33795432 Free PMC article.
Immunization with a self-assembling nanoparticle vaccine displaying EBV gH/gL protects humanized mice against lethal viral challenge.
Malhi H, Homad LJ, Wan YH, Poudel B, Fiala B, Borst AJ, Wang JY, Walkey C, Price J, Wall A, Singh S, Moodie Z, Carter L, Handa S, Correnti CE, Stoddard BL, Veesler D, Pancera M, Olson J, King NP, McGuire AT. Malhi H, et al. Among authors: homad lj. Cell Rep Med. 2022 Jun 21;3(6):100658. doi: 10.1016/j.xcrm.2022.100658. Epub 2022 Jun 14. Cell Rep Med. 2022. PMID: 35705092 Free PMC article.
18 results