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Ubiquitin-like protein 3 (UBL3) is required for MARCH ubiquitination of major histocompatibility complex class II and CD86.
Liu H, Wilson KR, Firth AM, Macri C, Schriek P, Blum AB, Villar J, Wormald S, Shambrook M, Xu B, Lim HJ, McWilliam HEG, Hill AF, Edgington-Mitchell LE, Caminschi I, Lahoud MH, Segura E, Herold MJ, Villadangos JA, Mintern JD. Liu H, et al. Among authors: lim hj. Nat Commun. 2022 Apr 11;13(1):1934. doi: 10.1038/s41467-022-29524-w. Nat Commun. 2022. PMID: 35411049 Free PMC article.
Absence of mucosal-associated invariant T cells in a person with a homozygous point mutation in MR1.
Howson LJ, Awad W, von Borstel A, Lim HJ, McWilliam HEG, Sandoval-Romero ML, Majumdar S, Hamzeh AR, Andrews TD, McDermott DH, Murphy PM, Le Nours J, Mak JYW, Liu L, Fairlie DP, McCluskey J, Villadangos JA, Cook MC, Turner SJ, Davey MS, Ojaimi S, Rossjohn J. Howson LJ, et al. Among authors: lim hj. Sci Immunol. 2020 Jul 24;5(49):eabc9492. doi: 10.1126/sciimmunol.abc9492. Sci Immunol. 2020. PMID: 32709702 Free PMC article.
Endoplasmic reticulum chaperones stabilize ligand-receptive MR1 molecules for efficient presentation of metabolite antigens.
McWilliam HEG, Mak JYW, Awad W, Zorkau M, Cruz-Gomez S, Lim HJ, Yan Y, Wormald S, Dagley LF, Eckle SBG, Corbett AJ, Liu H, Li S, Reddiex SJJ, Mintern JD, Liu L, McCluskey J, Rossjohn J, Fairlie DP, Villadangos JA. McWilliam HEG, et al. Among authors: lim hj. Proc Natl Acad Sci U S A. 2020 Oct 6;117(40):24974-24985. doi: 10.1073/pnas.2011260117. Epub 2020 Sep 21. Proc Natl Acad Sci U S A. 2020. PMID: 32958637 Free PMC article.
A specialized tyrosine-based endocytosis signal in MR1 controls antigen presentation to MAIT cells.
Lim HJ, Wubben JM, Garcia CP, Cruz-Gomez S, Deng J, Mak JYW, Hachani A, Anderson RJ, Painter GF, Goyette J, Amarasinghe SL, Ritchie ME, Roquilly A, Fairlie DP, Gaus K, Rossjohn J, Villadangos JA, McWilliam HEG. Lim HJ, et al. J Cell Biol. 2022 Dec 5;221(12):e202110125. doi: 10.1083/jcb.202110125. Epub 2022 Sep 21. J Cell Biol. 2022. PMID: 36129434 Free PMC article.
1,122 results