Poras H - Search Results

1

Dual enkephalinase inhibitor PL37 as a potential novel treatment of migraine: evidence from a rat model.

Descheemaeker A, Poras H, Wurm M, Luccarini P, Ouimet T, Dallel R. Descheemaeker A, et al. Among authors: poras h. Brain. 2022 Aug 27;145(8):2664-2670. doi: 10.1093/brain/awac139. Brain. 2022. PMID: 35411377

2

Detection and quantification of botulinum neurotoxin type a by a novel rapid in vitro fluorimetric assay.

Poras H, Ouimet T, Orng SV, Fournié-Zaluski MC, Popoff MR, Roques BP. Poras H, et al. Appl Environ Microbiol. 2009 Jul;75(13):4382-90. doi: 10.1128/AEM.00091-09. Epub 2009 May 8. Appl Environ Microbiol. 2009. PMID: 19429547 Free PMC article.

3

Identification of an endothelin-converting enzyme-2-specific fluorigenic substrate and development of an in vitro and ex vivo enzymatic assay.

Ouimet T, Orng SV, Poras H, Gagnidze K, Devi LA, Fournié-Zaluski MC, Roques BP. Ouimet T, et al. Among authors: poras h. J Biol Chem. 2010 Nov 5;285(45):34390-400. doi: 10.1074/jbc.M110.120576. Epub 2010 Aug 31. J Biol Chem. 2010. PMID: 20807771 Free PMC article.

4

Pluripotentialities of a quenched fluorescent peptide substrate library: enzymatic detection, characterization, and isoenzymes differentiation.

Poras H, Ouimet T, Orng SV, Dangé E, Fournié-Zaluski MC, Roques BP. Poras H, et al. Anal Biochem. 2011 Dec 15;419(2):95-105. doi: 10.1016/j.ab.2011.08.016. Epub 2011 Aug 16. Anal Biochem. 2011. PMID: 21893023

5

Highly sensitive quenched fluorescent substrate of Legionella major secretory protein (msp) based on its structural analysis.

Poras H, Duquesnoy S, Dange E, Pinon A, Vialette M, Fournié-Zaluski MC, Ouimet T. Poras H, et al. J Biol Chem. 2012 Jun 8;287(24):20221-30. doi: 10.1074/jbc.M111.334334. Epub 2012 Apr 23. J Biol Chem. 2012. PMID: 22528499 Free PMC article.

6

Comparison of fluorigenic peptide substrates PL50, SNAPTide, and BoTest A/E for BoNT/A detection and quantification: exosite binding confers high-assay sensitivity.

Ouimet T, Duquesnoy S, Poras H, Fournié-Zaluski MC, Roques BP. Ouimet T, et al. Among authors: poras h. J Biomol Screen. 2013 Jul;18(6):726-35. doi: 10.1177/1087057113476089. Epub 2013 Feb 20. J Biomol Screen. 2013. PMID: 23427044

7

A sensitive fluorigenic substrate for selective in vitro and in vivo assay of leukotriene A4 hydrolase activity.

Poras H, Duquesnoy S, Fournié-Zaluski MC, Ratinaud-Giraud C, Roques BP, Ouimet T. Poras H, et al. Anal Biochem. 2013 Oct 15;441(2):152-61. doi: 10.1016/j.ab.2013.06.016. Epub 2013 Jul 11. Anal Biochem. 2013. PMID: 23851339

8

New orally active dual enkephalinase inhibitors (DENKIs) for central and peripheral pain treatment.

Poras H, Bonnard E, Dangé E, Fournié-Zaluski MC, Roques BP. Poras H, et al. J Med Chem. 2014 Jul 10;57(13):5748-63. doi: 10.1021/jm500602h. Epub 2014 Jun 24. J Med Chem. 2014. PMID: 24927250

9

Preventive and alleviative effects of the dual enkephalinase inhibitor (Denki) PL265 in a murine model of neuropathic pain.

Bonnard E, Poras H, Fournié-Zaluski MC, Roques BP. Bonnard E, et al. Among authors: poras h. Eur J Pharmacol. 2016 Oct 5;788:176-182. doi: 10.1016/j.ejphar.2016.05.041. Epub 2016 Jun 4. Eur J Pharmacol. 2016. PMID: 27266667

10

Substituted α-mercaptoketones, new types of specific neprilysin inhibitors.

Poras H, Patouret R, Leiris S, Ouimet T, Fournié-Zaluski MC, Roques BP. Poras H, et al. Bioorg Med Chem Lett. 2017 Aug 15;27(16):3883-3890. doi: 10.1016/j.bmcl.2017.06.050. Epub 2017 Jun 21. Bioorg Med Chem Lett. 2017. PMID: 28676269

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