Conner KP - Search Results

1

Visualizing Spatial and Stoichiometric Barriers to Bispecific T-Cell Engager Efficacy.

You R, Artichoker J, Ray A, Gonzalez Velozo H, Rock DA, Conner KP, Krummel MF. You R, et al. Among authors: conner kp. Cancer Immunol Res. 2022 Jun 3;10(6):698-712. doi: 10.1158/2326-6066.CIR-21-0594. Cancer Immunol Res. 2022. PMID: 35413104 Free PMC article.

2

The biodistribution of therapeutic proteins: Mechanism, implications for pharmacokinetics, and methods of evaluation.

Conner KP, Devanaboyina SC, Thomas VA, Rock DA. Conner KP, et al. Pharmacol Ther. 2020 Aug;212:107574. doi: 10.1016/j.pharmthera.2020.107574. Epub 2020 May 17. Pharmacol Ther. 2020. PMID: 32433985 Review.

3

Evaluation of near infrared fluorescent labeling of monoclonal antibodies as a tool for tissue distribution.

Conner KP, Rock BM, Kwon GK, Balthasar JP, Abuqayyas L, Wienkers LC, Rock DA. Conner KP, et al. Drug Metab Dispos. 2014 Nov;42(11):1906-13. doi: 10.1124/dmd.114.060319. Epub 2014 Sep 10. Drug Metab Dispos. 2014. PMID: 25209366 Free PMC article.

4

Preclinical characterization of the ADME properties of a surrogate anti-IL-36R monoclonal antibody antagonist in mouse serum and tissues.

Conner KP, Pastuskovas CV, Soto M, Thomas VA, Wagner M, Rock DA. Conner KP, et al. MAbs. 2020 Jan-Dec;12(1):1746520. doi: 10.1080/19420862.2020.1746520. MAbs. 2020. PMID: 32310023 Free PMC article.

5

Use of Cryopreserved Hepatocytes as Part of an Integrated Strategy to Characterize In Vivo Clearance for Peptide-Antibody Conjugate Inhibitors of Nav1.7 in Preclinical Species.

Foti RS, Biswas K, Aral J, Be X, Berry L, Cheng Y, Conner K, Falsey JR, Glaus C, Herberich B, Hickman D, Ikotun T, Li H, Long J, Huang L, Miranda LP, Murray J, Moyer B, Netirojjanakul C, Nixey TE, Sham K, Soto M, Tegley CM, Tran L, Wu B, Yin L, Rock DA. Foti RS, et al. Drug Metab Dispos. 2019 Oct;47(10):1111-1121. doi: 10.1124/dmd.119.087742. Epub 2019 Aug 6. Drug Metab Dispos. 2019. PMID: 31387871

6

Altering Antibody-Drug Conjugate Binding to the Neonatal Fc Receptor Impacts Efficacy and Tolerability.

Hamblett KJ, Le T, Rock BM, Rock DA, Siu S, Huard JN, Conner KP, Milburn RR, O'Neill JW, Tometsko ME, Fanslow WC. Hamblett KJ, et al. Among authors: conner kp. Mol Pharm. 2016 Jul 5;13(7):2387-96. doi: 10.1021/acs.molpharmaceut.6b00153. Epub 2016 Jun 13. Mol Pharm. 2016. PMID: 27248573

7

Defining the Threshold IL-2 Signal Required for Induction of Selective Treg Cell Responses Using Engineered IL-2 Muteins.

Ghelani A, Bates D, Conner K, Wu MZ, Lu J, Hu YL, Li CM, Chaudhry A, Sohn SJ. Ghelani A, et al. Front Immunol. 2020 Jun 5;11:1106. doi: 10.3389/fimmu.2020.01106. eCollection 2020. Front Immunol. 2020. PMID: 32582190 Free PMC article.

8

Multiple drug binding modes in Mycobacterium tuberculosis CYP51B1.

Lockart MM, Butler JT, Mize CJ, Fair MN, Cruce AA, Conner KP, Atkins WM, Bowman MK. Lockart MM, et al. Among authors: conner kp. J Inorg Biochem. 2020 Apr;205:110994. doi: 10.1016/j.jinorgbio.2020.110994. Epub 2020 Jan 13. J Inorg Biochem. 2020. PMID: 31982812 Free PMC article.

9

Drug modulation of water-heme interactions in low-spin P450 complexes of CYP2C9d and CYP125A1.

Conner KP, Cruce AA, Krzyaniak MD, Schimpf AM, Frank DJ, Ortiz de Montellano P, Atkins WM, Bowman MK. Conner KP, et al. Biochemistry. 2015 Feb 10;54(5):1198-207. doi: 10.1021/bi501402k. Epub 2015 Jan 29. Biochemistry. 2015. PMID: 25591012 Free PMC article.

10

Interactions of cytochrome P450s with their ligands.

Conner KP, Woods CM, Atkins WM. Conner KP, et al. Arch Biochem Biophys. 2011 Mar 1;507(1):56-65. doi: 10.1016/j.abb.2010.10.006. Epub 2010 Oct 19. Arch Biochem Biophys. 2011. PMID: 20939998 Free PMC article. Review.

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