Thompson CH - Search Results

1

Cellular and behavioral effects of altered NaV1.2 sodium channel ion permeability in Scn2aK1422E mice.

Echevarria-Cooper DM, Hawkins NA, Misra SN, Huffman AM, Thaxton T, Thompson CH, Ben-Shalom R, Nelson AD, Lipkin AM, George AL Jr, Bender KJ, Kearney JA. Echevarria-Cooper DM, et al. Among authors: thompson ch. Hum Mol Genet. 2022 Aug 25;31(17):2964-2988. doi: 10.1093/hmg/ddac087. Hum Mol Genet. 2022. PMID: 35417922 Free PMC article.

2

SCN1A splice variants exhibit divergent sensitivity to commonly used antiepileptic drugs.

Thompson CH, Kahlig KM, George AL Jr. Thompson CH, et al. Epilepsia. 2011 May;52(5):1000-9. doi: 10.1111/j.1528-1167.2011.03040.x. Epub 2011 Mar 31. Epilepsia. 2011. PMID: 21453355 Free PMC article.

3

Nontruncating SCN1A mutations associated with severe myoclonic epilepsy of infancy impair cell surface expression.

Thompson CH, Porter JC, Kahlig KM, Daniels MA, George AL Jr. Thompson CH, et al. J Biol Chem. 2012 Dec 7;287(50):42001-8. doi: 10.1074/jbc.M112.421883. Epub 2012 Oct 19. J Biol Chem. 2012. PMID: 23086956 Free PMC article.

4

Selective targeting of gain-of-function KCNQ1 mutations predisposing to atrial fibrillation.

Campbell CM, Campbell JD, Thompson CH, Galimberti ES, Darbar D, Vanoye CG, George AL Jr. Campbell CM, et al. Among authors: thompson ch. Circ Arrhythm Electrophysiol. 2013 Oct;6(5):960-6. doi: 10.1161/CIRCEP.113.000439. Epub 2013 Sep 4. Circ Arrhythm Electrophysiol. 2013. PMID: 24006450 Free PMC article.

5

Strain- and age-dependent hippocampal neuron sodium currents correlate with epilepsy severity in Dravet syndrome mice.

Mistry AM, Thompson CH, Miller AR, Vanoye CG, George AL Jr, Kearney JA. Mistry AM, et al. Among authors: thompson ch. Neurobiol Dis. 2014 May;65:1-11. doi: 10.1016/j.nbd.2014.01.006. Epub 2014 Jan 14. Neurobiol Dis. 2014. PMID: 24434335 Free PMC article.

6

Antiepileptic activity of preferential inhibitors of persistent sodium current.

Anderson LL, Thompson CH, Hawkins NA, Nath RD, Petersohn AA, Rajamani S, Bush WS, Frankel WN, Vanoye CG, Kearney JA, George AL Jr. Anderson LL, et al. Among authors: thompson ch. Epilepsia. 2014 Aug;55(8):1274-83. doi: 10.1111/epi.12657. Epub 2014 May 23. Epilepsia. 2014. PMID: 24862204 Free PMC article.

7

Watch Out, No Brakes! Impaired Inhibition Results in Hyperexcitable Networks.

Thompson CH, Kearney JA. Thompson CH, et al. Epilepsy Curr. 2015 Nov-Dec;15(6):342-3. doi: 10.5698/1535-7511-15.6.342. Epilepsy Curr. 2015. PMID: 26633958 Free PMC article. No abstract available.

8

Cannabidiol Mellows Out Resurgent Sodium Current.

Thompson CH, Kearney JA. Thompson CH, et al. Epilepsy Curr. 2016 Nov-Dec;16(6):399-401. doi: 10.5698/1535-7511-16.6.399. Epilepsy Curr. 2016. PMID: 27857623 Free PMC article. No abstract available.

9

CaMKII modulates sodium current in neurons from epileptic Scn2a mutant mice.

Thompson CH, Hawkins NA, Kearney JA, George AL Jr. Thompson CH, et al. Proc Natl Acad Sci U S A. 2017 Feb 14;114(7):1696-1701. doi: 10.1073/pnas.1615774114. Epub 2017 Jan 30. Proc Natl Acad Sci U S A. 2017. PMID: 28137877 Free PMC article.

10

Unexpected Efficacy of a Novel Sodium Channel Modulator in Dravet Syndrome.

Anderson LL, Hawkins NA, Thompson CH, Kearney JA, George AL Jr. Anderson LL, et al. Among authors: thompson ch. Sci Rep. 2017 May 10;7(1):1682. doi: 10.1038/s41598-017-01851-9. Sci Rep. 2017. PMID: 28490751 Free PMC article.

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