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Mechanotransduction-induced glycolysis epigenetically regulates a CXCL1-dominant angiocrine signaling program in liver sinusoidal endothelial cells in vitro and in vivo.
Greuter T, Yaqoob U, Gan C, Jalan-Sakrikar N, Kostallari E, Lu J, Gao J, Sun L, Liu M, Sehrawat TS, Ibrahim SH, Furuta K, Nozickova K, Huang BQ, Gao B, Simons M, Cao S, Shah VH. Greuter T, et al. Among authors: gao j, gao b. J Hepatol. 2022 Sep;77(3):723-734. doi: 10.1016/j.jhep.2022.03.029. Epub 2022 Apr 12. J Hepatol. 2022. PMID: 35421427 Free PMC article.
Mechanical Stretch Increases Expression of CXCL1 in Liver Sinusoidal Endothelial Cells to Recruit Neutrophils, Generate Sinusoidal Microthombi, and Promote Portal Hypertension.
Hilscher MB, Sehrawat T, Arab JP, Zeng Z, Gao J, Liu M, Kostallari E, Gao Y, Simonetto DA, Yaqoob U, Cao S, Revzin A, Beyder A, Wang RA, Kamath PS, Kubes P, Shah VH. Hilscher MB, et al. Among authors: gao j, gao y. Gastroenterology. 2019 Jul;157(1):193-209.e9. doi: 10.1053/j.gastro.2019.03.013. Epub 2019 Mar 11. Gastroenterology. 2019. PMID: 30872106 Free PMC article.
GIPC-Regulated IGFBP-3 Promotes HSC Migration In Vitro and Portal Hypertension In Vivo Through a β1-Integrin Pathway.
Yaqoob U, Luo F, Greuter T, Jalan Sakrikar N, Sehrawat TS, Lu J, Hu X, Gao J, Kostallari E, Chen J, Arab JP, Martin-Mateos R, Cao S, Shah VH. Yaqoob U, et al. Among authors: gao j. Cell Mol Gastroenterol Hepatol. 2020;10(3):545-559. doi: 10.1016/j.jcmgh.2020.05.005. Epub 2020 May 22. Cell Mol Gastroenterol Hepatol. 2020. PMID: 32447051 Free PMC article.
Super enhancer regulation of cytokine-induced chemokine production in alcoholic hepatitis.
Liu M, Cao S, He L, Gao J, Arab JP, Cui H, Xuan W, Gao Y, Sehrawat TS, Hamdan FH, Ventura-Cots M, Argemi J, Pomerantz WCK, Johnsen SA, Lee JH, Gao F, Ordog T, Mathurin P, Revzin A, Bataller R, Yan H, Shah VH. Liu M, et al. Among authors: gao f, gao j, gao y. Nat Commun. 2021 Jul 27;12(1):4560. doi: 10.1038/s41467-021-24843-w. Nat Commun. 2021. PMID: 34315876 Free PMC article.
Stiffness is associated with hepatic stellate cell heterogeneity during liver fibrosis.
Kostallari E, Wei B, Sicard D, Li J, Cooper SA, Gao J, Dehankar M, Li Y, Cao S, Yin M, Tschumperlin DJ, Shah VH. Kostallari E, et al. Among authors: gao j. Am J Physiol Gastrointest Liver Physiol. 2022 Feb 1;322(2):G234-G246. doi: 10.1152/ajpgi.00254.2021. Epub 2021 Dec 23. Am J Physiol Gastrointest Liver Physiol. 2022. PMID: 34941452 Free PMC article.
Inflammasomes and Pyroptosis of Liver Cells in Liver Fibrosis.
Gan C, Cai Q, Tang C, Gao J. Gan C, et al. Among authors: gao j. Front Immunol. 2022 May 30;13:896473. doi: 10.3389/fimmu.2022.896473. eCollection 2022. Front Immunol. 2022. PMID: 35707547 Free PMC article. Review.
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