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PNA microprobe for label-free detection of expanded trinucleotide repeats.
Asefifeyzabadi N, Durocher G, Tshilenge KT, Alam T, Ellerby LM, Shamsi MH. Asefifeyzabadi N, et al. Among authors: ellerby lm. RSC Adv. 2022 Mar 10;12(13):7757-7761. doi: 10.1039/d2ra00230b. eCollection 2022 Mar 8. RSC Adv. 2022. PMID: 35424746 Free PMC article.
FOXO3 targets are reprogrammed as Huntington's disease neural cells and striatal neurons face senescence with p16INK4a increase.
Voisin J, Farina F, Naphade S, Fontaine M, Tshilenge KT, Galicia Aguirre C, Lopez-Ramirez A, Dancourt J, Ginisty A, Sasidharan Nair S, Lakshika Madushani K, Zhang N, Lejeune FX, Verny M, Campisi J, Ellerby LM, Neri C. Voisin J, et al. Among authors: ellerby lm. Aging Cell. 2020 Nov;19(11):e13226. doi: 10.1111/acel.13226. Epub 2020 Nov 6. Aging Cell. 2020. PMID: 33156570 Free PMC article.
Modulating FKBP5/FKBP51 and autophagy lowers HTT (huntingtin) levels.
Bailus BJ, Scheeler SM, Simons J, Sanchez MA, Tshilenge KT, Creus-Muncunill J, Naphade S, Lopez-Ramirez A, Zhang N, Lakshika Madushani K, Moroz S, Loureiro A, Schreiber KH, Hausch F, Kennedy BK, Ehrlich ME, Ellerby LM. Bailus BJ, et al. Among authors: ellerby lm. Autophagy. 2021 Dec;17(12):4119-4140. doi: 10.1080/15548627.2021.1904489. Epub 2021 May 24. Autophagy. 2021. PMID: 34024231 Free PMC article.
Unbiased identification of novel transcription factors in striatal compartmentation and striosome maturation.
Cirnaru MD, Song S, Tshilenge KT, Corwin C, Mleczko J, Galicia Aguirre C, Benlhabib H, Bendl J, Apontes P, Fullard J, Creus-Muncunill J, Reyahi A, Nik AM, Carlsson P, Roussos P, Mooney SD, Ellerby LM, Ehrlich ME. Cirnaru MD, et al. Among authors: ellerby lm. Elife. 2021 Oct 5;10:e65979. doi: 10.7554/eLife.65979. Elife. 2021. PMID: 34609283 Free PMC article.
Postnatal Conditional Deletion of Bcl11b in Striatal Projection Neurons Mimics the Transcriptional Signature of Huntington's Disease.
Song S, Creus Muncunill J, Galicia Aguirre C, Tshilenge KT, Hamilton BW, Gerencser AA, Benlhabib H, Cirnaru MD, Leid M, Mooney SD, Ellerby LM, Ehrlich ME. Song S, et al. Among authors: ellerby lm. Biomedicines. 2022 Sep 23;10(10):2377. doi: 10.3390/biomedicines10102377. Biomedicines. 2022. PMID: 36289639 Free PMC article.
iPSC-based drug screening for Huntington's disease.
Zhang N, Bailus BJ, Ring KL, Ellerby LM. Zhang N, et al. Among authors: ellerby lm. Brain Res. 2016 May 1;1638(Pt A):42-56. doi: 10.1016/j.brainres.2015.09.020. Epub 2015 Sep 30. Brain Res. 2016. PMID: 26428226 Free PMC article. Review.
111 results