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CHIR99021 causes inactivation of Tyrosine Hydroxylase and depletion of dopamine in rat brain striatum.
Neuropharmacology. 2024 Jan 1;242:109759. doi: 10.1016/j.neuropharm.2023.109759. Epub 2023 Oct 14.
Neuropharmacology. 2024.
PMID: 37844866
Free article.
Spontaneous changes in brain striatal dopamine synthesis and storage dynamics ex vivo reveal end-product feedback-inhibition of tyrosine hydroxylase.
González-Sepúlveda M, Omar MY, Hamdon S, Ma G, Rosell-Vilar S, Raivio N, Abass D, Martínez-Rivas A, Vila M, Giraldo J, Carrascal M, Abián J, Gil C, Sabriá J, Ortiz J, Moreno-Delgado D.
González-Sepúlveda M, et al. Among authors: hamdon s.
Neuropharmacology. 2022 Jul 1;212:109058. doi: 10.1016/j.neuropharm.2022.109058. Epub 2022 Apr 13.
Neuropharmacology. 2022.
PMID: 35429504
Free article.
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