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Development of a NanoBRET assay to validate inhibitors of Sirt2-mediated lysine deacetylation and defatty-acylation that block prostate cancer cell migration.
Vogelmann A, Schiedel M, Wössner N, Merz A, Herp D, Hammelmann S, Colcerasa A, Komaniecki G, Hong JY, Sum M, Metzger E, Neuwirt E, Zhang L, Einsle O, Groß O, Schüle R, Lin H, Sippl W, Jung M. Vogelmann A, et al. Among authors: hammelmann s. RSC Chem Biol. 2022 Mar 1;3(4):468-485. doi: 10.1039/d1cb00244a. eCollection 2022 Apr 6. RSC Chem Biol. 2022. PMID: 35441145 Free PMC article.
HaloTag-Targeted Sirtuin-Rearranging Ligand (SirReal) for the Development of Proteolysis-Targeting Chimeras (PROTACs) against the Lysine Deacetylase Sirtuin 2 (Sirt2)*.
Schiedel M, Lehotzky A, Szunyogh S, Oláh J, Hammelmann S, Wössner N, Robaa D, Einsle O, Sippl W, Ovádi J, Jung M. Schiedel M, et al. Among authors: hammelmann s. Chembiochem. 2020 Dec 1;21(23):3371-3376. doi: 10.1002/cbic.202000351. Epub 2020 Aug 27. Chembiochem. 2020. PMID: 32672888 Free PMC article.