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Development of a NanoBRET assay to validate inhibitors of Sirt2-mediated lysine deacetylation and defatty-acylation that block prostate cancer cell migration.
Vogelmann A, Schiedel M, Wössner N, Merz A, Herp D, Hammelmann S, Colcerasa A, Komaniecki G, Hong JY, Sum M, Metzger E, Neuwirt E, Zhang L, Einsle O, Groß O, Schüle R, Lin H, Sippl W, Jung M. Vogelmann A, et al. Among authors: lin h. RSC Chem Biol. 2022 Mar 1;3(4):468-485. doi: 10.1039/d1cb00244a. eCollection 2022 Apr 6. RSC Chem Biol. 2022. PMID: 35441145 Free PMC article.
HPLC-Based Enzyme Assays for Sirtuins.
Hong JY, Zhang X, Lin H. Hong JY, et al. Among authors: lin h. Methods Mol Biol. 2018;1813:225-234. doi: 10.1007/978-1-4939-8588-3_15. Methods Mol Biol. 2018. PMID: 30097871 Free PMC article.
Updates on the epigenetic roles of sirtuins.
Kosciuk T, Wang M, Hong JY, Lin H. Kosciuk T, et al. Among authors: lin h. Curr Opin Chem Biol. 2019 Aug;51:18-29. doi: 10.1016/j.cbpa.2019.01.023. Epub 2019 Mar 12. Curr Opin Chem Biol. 2019. PMID: 30875552 Free PMC article. Review.
Activity-Guided Design of HDAC11-Specific Inhibitors.
Son SI, Cao J, Zhu CL, Miller SP, Lin H. Son SI, et al. Among authors: lin h. ACS Chem Biol. 2019 Jul 19;14(7):1393-1397. doi: 10.1021/acschembio.9b00292. Epub 2019 Jul 2. ACS Chem Biol. 2019. PMID: 31264832 Free PMC article.
SIRT2 and Lysine Fatty Acylation Regulate the Activity of RalB and Cell Migration.
Spiegelman NA, Zhang X, Jing H, Cao J, Kotliar IB, Aramsangtienchai P, Wang M, Tong Z, Rosch KM, Lin H. Spiegelman NA, et al. Among authors: lin h. ACS Chem Biol. 2019 Sep 20;14(9):2014-2023. doi: 10.1021/acschembio.9b00492. Epub 2019 Sep 3. ACS Chem Biol. 2019. PMID: 31433161 Free PMC article.
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