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Targeting a single function of the multifunctional matrix metalloprotease MT1-MMP: impact on lymphangiogenesis.
Ingvarsen S, Porse A, Erpicum C, Maertens L, Jürgensen HJ, Madsen DH, Melander MC, Gårdsvoll H, Høyer-Hansen G, Noel A, Holmbeck K, Engelholm LH, Behrendt N. Ingvarsen S, et al. Among authors: holmbeck k. J Biol Chem. 2013 Apr 12;288(15):10195-204. doi: 10.1074/jbc.M112.447169. Epub 2013 Feb 14. J Biol Chem. 2013. PMID: 23413031 Free PMC article.
Extracellular collagenases and the endocytic receptor, urokinase plasminogen activator receptor-associated protein/Endo180, cooperate in fibroblast-mediated collagen degradation.
Madsen DH, Engelholm LH, Ingvarsen S, Hillig T, Wagenaar-Miller RA, Kjøller L, Gårdsvoll H, Høyer-Hansen G, Holmbeck K, Bugge TH, Behrendt N. Madsen DH, et al. Among authors: holmbeck k. J Biol Chem. 2007 Sep 14;282(37):27037-27045. doi: 10.1074/jbc.M701088200. Epub 2007 Jul 9. J Biol Chem. 2007. PMID: 17623673 Free article.
A CCR2 macrophage endocytic pathway mediates extravascular fibrin clearance in vivo.
Motley MP, Madsen DH, Jürgensen HJ, Spencer DE, Szabo R, Holmbeck K, Flick MJ, Lawrence DA, Castellino FJ, Weigert R, Bugge TH. Motley MP, et al. Among authors: holmbeck k. Blood. 2016 Mar 3;127(9):1085-96. doi: 10.1182/blood-2015-05-644260. Epub 2015 Dec 8. Blood. 2016. PMID: 26647393 Free PMC article.
M2-like macrophages are responsible for collagen degradation through a mannose receptor-mediated pathway.
Madsen DH, Leonard D, Masedunskas A, Moyer A, Jürgensen HJ, Peters DE, Amornphimoltham P, Selvaraj A, Yamada SS, Brenner DA, Burgdorf S, Engelholm LH, Behrendt N, Holmbeck K, Weigert R, Bugge TH. Madsen DH, et al. Among authors: holmbeck k. J Cell Biol. 2013 Sep 16;202(6):951-66. doi: 10.1083/jcb.201301081. Epub 2013 Sep 9. J Cell Biol. 2013. PMID: 24019537 Free PMC article.
75 results