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SARS-CoV-2 productively infects primary human immune system cells in vitro and in COVID-19 patients.
Pontelli MC, Castro ÍA, Martins RB, La Serra L, Veras FP, Nascimento DC, Silva CM, Cardoso RS, Rosales R, Gomes R, Lima TM, Souza JP, Vitti BC, Caetité DB, de Lima MHF, Stumpf SD, Thompson CE, Bloyet LM, Toller-Kawahisa JE, Giannini MC, Bonjorno LP, Lopes MIF, Batah SS, Siyuan L, Luppino-Assad R, Almeida SCL, Oliveira FR, Benatti MN, Pontes LLF, Santana RC, Vilar FC, Auxiliadora-Martins M, Shi PY, Cunha TM, Calado RT, Alves-Filho JC, Zamboni DS, Fabro AT, Louzada-Junior P, Oliveira RDR, Whelan SPJ, Cunha FQ, Arruda E. Pontelli MC, et al. Among authors: shi py. J Mol Cell Biol. 2022 Aug 17;14(4):mjac021. doi: 10.1093/jmcb/mjac021. J Mol Cell Biol. 2022. PMID: 35451490 Free PMC article.
An Infectious cDNA Clone of SARS-CoV-2.
Xie X, Muruato A, Lokugamage KG, Narayanan K, Zhang X, Zou J, Liu J, Schindewolf C, Bopp NE, Aguilar PV, Plante KS, Weaver SC, Makino S, LeDuc JW, Menachery VD, Shi PY. Xie X, et al. Among authors: shi py. Cell Host Microbe. 2020 May 13;27(5):841-848.e3. doi: 10.1016/j.chom.2020.04.004. Epub 2020 Apr 13. Cell Host Microbe. 2020. PMID: 32289263 Free PMC article.
In vivo antiviral host transcriptional response to SARS-CoV-2 by viral load, sex, and age.
Lieberman NAP, Peddu V, Xie H, Shrestha L, Huang ML, Mears MC, Cajimat MN, Bente DA, Shi PY, Bovier F, Roychoudhury P, Jerome KR, Moscona A, Porotto M, Greninger AL. Lieberman NAP, et al. Among authors: shi py. PLoS Biol. 2020 Sep 8;18(9):e3000849. doi: 10.1371/journal.pbio.3000849. eCollection 2020 Sep. PLoS Biol. 2020. PMID: 32898168 Free PMC article.
Evasion of Type I Interferon by SARS-CoV-2.
Xia H, Cao Z, Xie X, Zhang X, Chen JY, Wang H, Menachery VD, Rajsbaum R, Shi PY. Xia H, et al. Among authors: shi py. Cell Rep. 2020 Oct 6;33(1):108234. doi: 10.1016/j.celrep.2020.108234. Epub 2020 Sep 19. Cell Rep. 2020. PMID: 32979938 Free PMC article.
Engineering SARS-CoV-2 using a reverse genetic system.
Xie X, Lokugamage KG, Zhang X, Vu MN, Muruato AE, Menachery VD, Shi PY. Xie X, et al. Among authors: shi py. Nat Protoc. 2021 Mar;16(3):1761-1784. doi: 10.1038/s41596-021-00491-8. Epub 2021 Jan 29. Nat Protoc. 2021. PMID: 33514944 Free PMC article. Review.
A modified vaccinia Ankara vector-based vaccine protects macaques from SARS-CoV-2 infection, immune pathology, and dysfunction in the lungs.
Routhu NK, Cheedarla N, Gangadhara S, Bollimpelli VS, Boddapati AK, Shiferaw A, Rahman SA, Sahoo A, Edara VV, Lai L, Floyd K, Wang S, Fischinger S, Atyeo C, Shin SA, Gumber S, Kirejczyk S, Cohen J, Jean SM, Wood JS, Connor-Stroud F, Stammen RL, Upadhyay AA, Pellegrini K, Montefiori D, Shi PY, Menachery VD, Alter G, Vanderford TH, Bosinger SE, Suthar MS, Amara RR. Routhu NK, et al. Among authors: shi py. Immunity. 2021 Mar 9;54(3):542-556.e9. doi: 10.1016/j.immuni.2021.02.001. Epub 2021 Feb 4. Immunity. 2021. PMID: 33631118 Free PMC article.
In vivo monoclonal antibody efficacy against SARS-CoV-2 variant strains.
Diamond M, Chen R, Winkler E, Case J, Aziati I, Bricker T, Joshi A, Darling T, Ying B, Errico J, Shrihari S, VanBlargan L, Xie X, Gilchuk P, Zost S, Droit L, Liu Z, Stumpf S, Wang D, Handley S, Stine W, Shi PY, Garcia-Knight M, Andino R, Chiu C, Ellebedy A, Fremont D, Whelan S, Crowe J, Purcell L, Corti D, Boon A. Diamond M, et al. Among authors: shi py. Res Sq [Preprint]. 2021 Apr 23:rs.3.rs-448370. doi: 10.21203/rs.3.rs-448370/v1. Res Sq. 2021. Update in: Nature. 2021 Aug;596(7870):103-108. doi: 10.1038/s41586-021-03720-y PMID: 34013259 Free PMC article. Updated. Preprint.
In vivo monoclonal antibody efficacy against SARS-CoV-2 variant strains.
Chen RE, Winkler ES, Case JB, Aziati ID, Bricker TL, Joshi A, Darling TL, Ying B, Errico JM, Shrihari S, VanBlargan LA, Xie X, Gilchuk P, Zost SJ, Droit L, Liu Z, Stumpf S, Wang D, Handley SA, Stine WB Jr, Shi PY, Davis-Gardner ME, Suthar MS, Knight MG, Andino R, Chiu CY, Ellebedy AH, Fremont DH, Whelan SPJ, Crowe JE Jr, Purcell L, Corti D, Boon ACM, Diamond MS. Chen RE, et al. Among authors: shi py. Nature. 2021 Aug;596(7870):103-108. doi: 10.1038/s41586-021-03720-y. Epub 2021 Jun 21. Nature. 2021. PMID: 34153975 Free PMC article.
Attenuated activation of pulmonary immune cells in mRNA-1273-vaccinated hamsters after SARS-CoV-2 infection.
Meyer M, Wang Y, Edwards D, Smith GR, Rubenstein AB, Ramanathan P, Mire CE, Pietzsch C, Chen X, Ge Y, Cheng WS, Henry C, Woods A, Ma L, Stewart-Jones GB, Bock KW, Minai M, Nagata BM, Periasamy S, Shi PY, Graham BS, Moore IN, Ramos I, Troyanskaya OG, Zaslavsky E, Carfi A, Sealfon SC, Bukreyev A. Meyer M, et al. Among authors: shi py. J Clin Invest. 2021 Oct 15;131(20):e148036. doi: 10.1172/JCI148036. J Clin Invest. 2021. PMID: 34449440 Free PMC article.
479 results