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Mutant IDH1 is required for IDH1 mutated tumor cell growth.
Jin G, Pirozzi CJ, Chen LH, Lopez GY, Duncan CG, Feng J, Spasojevic I, Bigner DD, He Y, Yan H. Jin G, et al. Among authors: he y. Oncotarget. 2012 Aug;3(8):774-82. doi: 10.18632/oncotarget.577. Oncotarget. 2012. PMID: 22885298 Free PMC article.
Global identification of MLL2-targeted loci reveals MLL2's role in diverse signaling pathways.
Guo C, Chang CC, Wortham M, Chen LH, Kernagis DN, Qin X, Cho YW, Chi JT, Grant GA, McLendon RE, Yan H, Ge K, Papadopoulos N, Bigner DD, He Y. Guo C, et al. Among authors: he y. Proc Natl Acad Sci U S A. 2012 Oct 23;109(43):17603-8. doi: 10.1073/pnas.1208807109. Epub 2012 Oct 8. Proc Natl Acad Sci U S A. 2012. PMID: 23045699 Free PMC article.
The genetic landscape of anaplastic astrocytoma.
Killela PJ, Pirozzi CJ, Reitman ZJ, Jones S, Rasheed BA, Lipp E, Friedman H, Friedman AH, He Y, McLendon RE, Bigner DD, Yan H. Killela PJ, et al. Among authors: he y. Oncotarget. 2014 Mar 30;5(6):1452-7. doi: 10.18632/oncotarget.1505. Oncotarget. 2014. PMID: 24140581 Free PMC article.
Mutations in IDH1, IDH2, and in the TERT promoter define clinically distinct subgroups of adult malignant gliomas.
Killela PJ, Pirozzi CJ, Healy P, Reitman ZJ, Lipp E, Rasheed BA, Yang R, Diplas BH, Wang Z, Greer PK, Zhu H, Wang CY, Carpenter AB, Friedman H, Friedman AH, Keir ST, He J, He Y, McLendon RE, Herndon JE 2nd, Yan H, Bigner DD. Killela PJ, et al. Among authors: he y, he j. Oncotarget. 2014 Mar 30;5(6):1515-25. doi: 10.18632/oncotarget.1765. Oncotarget. 2014. PMID: 24722048 Free PMC article.
Exome sequencing identifies somatic gain-of-function PPM1D mutations in brainstem gliomas.
Zhang L, Chen LH, Wan H, Yang R, Wang Z, Feng J, Yang S, Jones S, Wang S, Zhou W, Zhu H, Killela PJ, Zhang J, Wu Z, Li G, Hao S, Wang Y, Webb JB, Friedman HS, Friedman AH, McLendon RE, He Y, Reitman ZJ, Bigner DD, Yan H. Zhang L, et al. Among authors: he y. Nat Genet. 2014 Jul;46(7):726-30. doi: 10.1038/ng.2995. Epub 2014 Jun 1. Nat Genet. 2014. PMID: 24880341 Free PMC article.
Mutant IDH1 Disrupts the Mouse Subventricular Zone and Alters Brain Tumor Progression.
Pirozzi CJ, Carpenter AB, Waitkus MS, Wang CY, Zhu H, Hansen LJ, Chen LH, Greer PK, Feng J, Wang Y, Bock CB, Fan P, Spasojevic I, McLendon RE, Bigner DD, He Y, Yan H. Pirozzi CJ, et al. Among authors: he y. Mol Cancer Res. 2017 May;15(5):507-520. doi: 10.1158/1541-7786.MCR-16-0485. Epub 2017 Feb 1. Mol Cancer Res. 2017. PMID: 28148827 Free PMC article.
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