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Novel structural insights for a pair of monoclonal antibodies recognizing non-overlapping epitopes of the glucosyltransferase domain of Clostridium difficile toxin B.
Liu J, Kothe M, Zhang J, Oloo E, Stegalkina S, Mundle ST, Li L, Zhang J, Cole LE, Barone L, Biemann HP, Kleanthous H, Anosova NG, Anderson SF. Liu J, et al. Among authors: biemann hp. Curr Res Struct Biol. 2022 Apr 7;4:96-105. doi: 10.1016/j.crstbi.2022.03.003. eCollection 2022. Curr Res Struct Biol. 2022. PMID: 35469152 Free PMC article.
The discovery of novel benzofuran-2-carboxylic acids as potent Pim-1 inhibitors.
Xiang Y, Hirth B, Asmussen G, Biemann HP, Bishop KA, Good A, Fitzgerald M, Gladysheva T, Jain A, Jancsics K, Liu J, Metz M, Papoulis A, Skerlj R, Stepp JD, Wei RR. Xiang Y, et al. Among authors: biemann hp. Bioorg Med Chem Lett. 2011 May 15;21(10):3050-6. doi: 10.1016/j.bmcl.2011.03.030. Epub 2011 Mar 16. Bioorg Med Chem Lett. 2011. PMID: 21507633
SCD1 inhibition causes cancer cell death by depleting mono-unsaturated fatty acids.
Mason P, Liang B, Li L, Fremgen T, Murphy E, Quinn A, Madden SL, Biemann HP, Wang B, Cohen A, Komarnitsky S, Jancsics K, Hirth B, Cooper CG, Lee E, Wilson S, Krumbholz R, Schmid S, Xiang Y, Booker M, Lillie J, Carter K. Mason P, et al. Among authors: biemann hp. PLoS One. 2012;7(3):e33823. doi: 10.1371/journal.pone.0033823. Epub 2012 Mar 22. PLoS One. 2012. PMID: 22457791 Free PMC article.
Knockdown of human deubiquitinase PSMD14 induces cell cycle arrest and senescence.
Byrne A, McLaren RP, Mason P, Chai L, Dufault MR, Huang Y, Liang B, Gans JD, Zhang M, Carter K, Gladysheva TB, Teicher BA, Biemann HP, Booker M, Goldberg MA, Klinger KW, Lillie J, Madden SL, Jiang Y. Byrne A, et al. Among authors: biemann hp. Exp Cell Res. 2010 Jan 15;316(2):258-71. doi: 10.1016/j.yexcr.2009.08.018. Epub 2009 Sep 2. Exp Cell Res. 2010. PMID: 19732767
18 results