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Page 1
TRAF3 alterations are frequent in del-3'IGH chronic lymphocytic leukemia patients and define a specific subgroup with adverse clinical features.
Pérez-Carretero C, Hernández-Sánchez M, González T, Quijada-Álamo M, Martín-Izquierdo M, Santos-Mínguez S, Miguel-García C, Vidal MJ, García-De-Coca A, Galende J, Pardal E, Aguilar C, Vargas-Pabón M, Dávila J, Gascón-Y-Marín I, Hernández-Rivas JÁ, Benito R, Hernández-Rivas JM, Rodríguez-Vicente AE. Pérez-Carretero C, et al. Among authors: quijada alamo m. Am J Hematol. 2022 Jul;97(7):903-914. doi: 10.1002/ajh.26578. Epub 2022 May 9. Am J Hematol. 2022. PMID: 35472012 Free article.
Next-generation sequencing and FISH studies reveal the appearance of gene mutations and chromosomal abnormalities in hematopoietic progenitors in chronic lymphocytic leukemia.
Quijada-Álamo M, Hernández-Sánchez M, Robledo C, Hernández-Sánchez JM, Benito R, Montaño A, Rodríguez-Vicente AE, Quwaider D, Martín AÁ, García-Álvarez M, Vidal-Manceñido MJ, Ferrer-Garrido G, Delgado-Beltrán MP, Galende J, Rodríguez JN, Martín-Núñez G, Alonso JM, García de Coca A, Queizán JA, Sierra M, Aguilar C, Kohlmann A, Hernández JÁ, González M, Hernández-Rivas JM. Quijada-Álamo M, et al. J Hematol Oncol. 2017 Apr 11;10(1):83. doi: 10.1186/s13045-017-0450-y. J Hematol Oncol. 2017. PMID: 28399885 Free PMC article.
Mutations in TP53 and JAK2 are independent prognostic biomarkers in B-cell precursor acute lymphoblastic leukaemia.
Forero-Castro M, Robledo C, Benito R, Bodega-Mayor I, Rapado I, Hernández-Sánchez M, Abáigar M, Maria Hernández-Sánchez J, Quijada-Álamo M, María Sánchez-Pina J, Sala-Valdés M, Araujo-Silva F, Kohlmann A, Luis Fuster J, Arefi M, de Las Heras N, Riesco S, Rodríguez JN, Hermosín L, Ribera J, Camos Guijosa M, Ramírez M, de Heredia Rubio CD, Barragán E, Martínez J, Ribera JM, Fernández-Ruiz E, Hernández-Rivas JM. Forero-Castro M, et al. Br J Cancer. 2017 Jul 11;117(2):256-265. doi: 10.1038/bjc.2017.152. Epub 2017 May 30. Br J Cancer. 2017. PMID: 28557976 Free PMC article.
CLL cells cumulate genetic aberrations prior to the first therapy even in outwardly inactive disease phase.
Hernández-Sánchez M, Kotaskova J, Rodríguez AE, Radova L, Tamborero D, Abáigar M, Plevova K, Benito R, Tom N, Quijada-Álamo M, Bikos V, Martín AÁ, Pal K, García de Coca A, Doubek M, López-Bigas N, Hernández-Rivas JM, Pospisilova S. Hernández-Sánchez M, et al. Leukemia. 2019 Feb;33(2):518-558. doi: 10.1038/s41375-018-0255-1. Epub 2018 Sep 12. Leukemia. 2019. PMID: 30209402 Free PMC article. No abstract available.
DNA damage response-related alterations define the genetic background of patients with chronic lymphocytic leukemia and chromosomal gains.
Hernández-Sánchez M, Rodríguez-Vicente AE, González-Gascón Y Marín I, Quijada-Álamo M, Hernández-Sánchez JM, Martín-Izquierdo M, Hernández-Rivas JÁ, Benito R, Hernández-Rivas JM. Hernández-Sánchez M, et al. Exp Hematol. 2019 Apr;72:9-13. doi: 10.1016/j.exphem.2019.02.003. Epub 2019 Feb 23. Exp Hematol. 2019. PMID: 30807786 Free article.
CRISPR/Cas9-generated models uncover therapeutic vulnerabilities of del(11q) CLL cells to dual BCR and PARP inhibition.
Quijada-Álamo M, Hernández-Sánchez M, Alonso-Pérez V, Rodríguez-Vicente AE, García-Tuñón I, Martín-Izquierdo M, Hernández-Sánchez JM, Herrero AB, Bastida JM, San Segundo L, Gruber M, García JL, Yin S, Ten Hacken E, Benito R, Ordóñez JL, Wu CJ, Hernández-Rivas JM. Quijada-Álamo M, et al. Leukemia. 2020 Jun;34(6):1599-1612. doi: 10.1038/s41375-020-0714-3. Epub 2020 Jan 23. Leukemia. 2020. PMID: 31974435 Free PMC article.
Prognosis Assessment of Early-Stage Chronic Lymphocytic Leukemia: Are We Ready to Predict Clinical Evolution Without a Crystal Ball?
González-Gascón-Y-Marín I, Muñoz-Novas C, Figueroa I, Hernández-Sánchez M, Rodríguez-Vicente AE, Quijada-Álamo M, Pérez-Carretero C, Moreno C, Collado R, Espinet B, Puiggros A, Heras NL, Bosch F, Hernández JÁ; Grupo Español de Leucemia Linfática Crónica and Grupo Cooperativo Español de Citogenética Hematológica. González-Gascón-Y-Marín I, et al. Clin Lymphoma Myeloma Leuk. 2020 Aug;20(8):548-555.e4. doi: 10.1016/j.clml.2020.03.003. Epub 2020 Apr 13. Clin Lymphoma Myeloma Leuk. 2020. PMID: 32389671
Chronic lymphocytic leukemia patients with IGH translocations are characterized by a distinct genetic landscape with prognostic implications.
Pérez-Carretero C, Hernández-Sánchez M, González T, Quijada-Álamo M, Martín-Izquierdo M, Hernández-Sánchez JM, Vidal MJ, de Coca AG, Aguilar C, Vargas-Pabón M, Alonso S, Sierra M, Rubio-Martínez A, Dávila J, Díaz-Valdés JR, Queizán JA, Hernández-Rivas JÁ, Benito R, Rodríguez-Vicente AE, Hernández-Rivas JM. Pérez-Carretero C, et al. Int J Cancer. 2020 Nov 15;147(10):2780-2792. doi: 10.1002/ijc.33235. Epub 2020 Sep 4. Int J Cancer. 2020. PMID: 32720348
Dissecting the role of TP53 alterations in del(11q) chronic lymphocytic leukemia.
Quijada-Álamo M, Pérez-Carretero C, Hernández-Sánchez M, Rodríguez-Vicente AE, Herrero AB, Hernández-Sánchez JM, Martín-Izquierdo M, Santos-Mínguez S, Del Rey M, González T, Rubio-Martínez A, García de Coca A, Dávila-Valls J, Hernández-Rivas JÁ, Parker H, Strefford JC, Benito R, Ordóñez JL, Hernández-Rivas JM. Quijada-Álamo M, et al. Clin Transl Med. 2021 Feb;11(2):e304. doi: 10.1002/ctm2.304. Clin Transl Med. 2021. PMID: 33634999 Free PMC article.
From Biomarkers to Models in the Changing Landscape of Chronic Lymphocytic Leukemia: Evolve or Become Extinct.
González-Gascón-Y-Marín I, Muñoz-Novas C, Rodríguez-Vicente AE, Quijada-Álamo M, Hernández-Sánchez M, Pérez-Carretero C, Ramos-Ascanio V, Hernández-Rivas JÁ. González-Gascón-Y-Marín I, et al. Among authors: quijada alamo m. Cancers (Basel). 2021 Apr 8;13(8):1782. doi: 10.3390/cancers13081782. Cancers (Basel). 2021. PMID: 33917885 Free PMC article. Review.
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