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A neutralizing antibody target in early HIV-1 infection was recapitulated in rhesus macaques immunized with the transmitted/founder envelope sequence.
Welbourn S, Chakraborty S, Yang JE, Gleinich AS, Gangadhara S, Khan S, Ferrebee C, Yagnik B, Burton S, Charles T, Smith SA, Williams D, Mopuri R, Upadhyay AA, Thompson J, Price MA, Wang S, Qin Z, Shen X, Williams LD, Eisel N, Peters T, Zhang L, Kilembe W, Karita E, Tomaras GD, Bosinger SE, Amara RR, Azadi P, Wright ER, Gnanakaran S, Derdeyn CA. Welbourn S, et al. Among authors: gnanakaran s. PLoS Pathog. 2022 May 3;18(5):e1010488. doi: 10.1371/journal.ppat.1010488. eCollection 2022 May. PLoS Pathog. 2022. PMID: 35503780 Free PMC article.
Unique mutational patterns in the envelope alpha 2 amphipathic helix and acquisition of length in gp120 hypervariable domains are associated with resistance to autologous neutralization of subtype C human immunodeficiency virus type 1.
Rong R, Gnanakaran S, Decker JM, Bibollet-Ruche F, Taylor J, Sfakianos JN, Mokili JL, Muldoon M, Mulenga J, Allen S, Hahn BH, Shaw GM, Blackwell JL, Korber BT, Hunter E, Derdeyn CA. Rong R, et al. Among authors: gnanakaran s. J Virol. 2007 Jun;81(11):5658-68. doi: 10.1128/JVI.00257-07. Epub 2007 Mar 14. J Virol. 2007. PMID: 17360739 Free PMC article.
Appreciating HIV type 1 diversity: subtype differences in Env.
Lynch RM, Shen T, Gnanakaran S, Derdeyn CA. Lynch RM, et al. Among authors: gnanakaran s. AIDS Res Hum Retroviruses. 2009 Mar;25(3):237-48. doi: 10.1089/aid.2008.0219. AIDS Res Hum Retroviruses. 2009. PMID: 19327047 Free PMC article.
Identification of amino acid substitutions associated with neutralization phenotype in the human immunodeficiency virus type-1 subtype C gp120.
Kirchherr JL, Hamilton J, Lu X, Gnanakaran S, Muldoon M, Daniels M, Kasongo W, Chalwe V, Mulenga C, Mwananyanda L, Musonda RM, Yuan X, Montefiori DC, Korber BT, Haynes BF, Gao F. Kirchherr JL, et al. Among authors: gnanakaran s. Virology. 2011 Jan 20;409(2):163-74. doi: 10.1016/j.virol.2010.09.031. Epub 2010 Oct 30. Virology. 2011. PMID: 21036380 Free PMC article.
120 results