Armen RS - Search Results

1

AKT inhibition in the central nervous system induces signaling defects resulting in psychiatric symptomatology.

Tsimberidou AM, Skliris A, Valentine A, Shaw J, Hering U, Vo HH, Chan TO, Armen RS, Cottrell JR, Pan JQ, Tsichlis PN. Tsimberidou AM, et al. Among authors: armen rs. Cell Biosci. 2022 May 7;12(1):56. doi: 10.1186/s13578-022-00793-8. Cell Biosci. 2022. PMID: 35525984 Free PMC article.

2

Resistance of Akt kinases to dephosphorylation through ATP-dependent conformational plasticity.

Chan TO, Zhang J, Rodeck U, Pascal JM, Armen RS, Spring M, Dumitru CD, Myers V, Li X, Cheung JY, Feldman AM. Chan TO, et al. Among authors: armen rs. Proc Natl Acad Sci U S A. 2011 Nov 15;108(46):E1120-7. doi: 10.1073/pnas.1109879108. Epub 2011 Oct 26. Proc Natl Acad Sci U S A. 2011. PMID: 22031698 Free PMC article.

3

Autoregulation of kinase dephosphorylation by ATP binding in AGC protein kinases.

Chan TO, Pascal JM, Armen RS, Rodeck U. Chan TO, et al. Among authors: armen rs. Cell Cycle. 2012 Feb 1;11(3):475-8. doi: 10.4161/cc.11.3.19059. Epub 2012 Feb 1. Cell Cycle. 2012. PMID: 22262182 Free PMC article. Review.

4

Akt kinase C-terminal modifications control activation loop dephosphorylation and enhance insulin response.

Chan TO, Zhang J, Tiegs BC, Blumhof B, Yan L, Keny N, Penny M, Li X, Pascal JM, Armen RS, Rodeck U, Penn RB. Chan TO, et al. Among authors: armen rs. Biochem J. 2015 Oct 1;471(1):37-51. doi: 10.1042/BJ20150325. Epub 2015 Jul 22. Biochem J. 2015. PMID: 26201515 Free PMC article.

5

A tripartite cooperative mechanism confers resistance of the protein kinase A catalytic subunit to dephosphorylation.

Chan TO, Armen RS, Yadav S, Shah S, Zhang J, Tiegs BC, Keny N, Blumhof B, Deshpande DA, Rodeck U, Penn RB. Chan TO, et al. Among authors: armen rs. J Biol Chem. 2020 Mar 6;295(10):3316-3329. doi: 10.1074/jbc.RA119.010004. Epub 2020 Jan 21. J Biol Chem. 2020. PMID: 31964716 Free PMC article.

6

Research Progress on Spike-Dependent SARS-CoV-2 Fusion Inhibitors and Small Molecules Targeting the S2 Subunit of Spike.

Freidel MR, Armen RS. Freidel MR, et al. Among authors: armen rs. Viruses. 2024 Apr 30;16(5):712. doi: 10.3390/v16050712. Viruses. 2024. PMID: 38793593 Free PMC article. Review.

7

Identification of the functional binding pocket for compounds targeting small-conductance Ca²⁺-activated potassium channels.

Zhang M, Pascal JM, Schumann M, Armen RS, Zhang JF. Zhang M, et al. Among authors: armen rs. Nat Commun. 2012;3:1021. doi: 10.1038/ncomms2017. Nat Commun. 2012. PMID: 22929778 Free PMC article.

8

Identification of distant drug off-targets by direct superposition of binding pocket surfaces.

Schumann M, Armen RS. Schumann M, et al. Among authors: armen rs. PLoS One. 2013 Dec 31;8(12):e83533. doi: 10.1371/journal.pone.0083533. eCollection 2013. PLoS One. 2013. PMID: 24391782 Free PMC article.

9

Structural Implications for Selective Targeting of PARPs.

Steffen JD, Brody JR, Armen RS, Pascal JM. Steffen JD, et al. Among authors: armen rs. Front Oncol. 2013 Dec 20;3:301. doi: 10.3389/fonc.2013.00301. Front Oncol. 2013. PMID: 24392349 Free PMC article. Review.

10

Systematic and efficient side chain optimization for molecular docking using a cheapest-path procedure.

Schumann M, Armen RS. Schumann M, et al. Among authors: armen rs. J Comput Chem. 2013 May 30;34(14):1258-69. doi: 10.1002/jcc.23251. Epub 2013 Feb 19. J Comput Chem. 2013. PMID: 23420703

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