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Development, Characterization, and in vivo Validation of a Humanized C6 Monoclonal Antibody that Inhibits the Membrane Attack Complex.
Gytz Olesen H, Michailidou I, Zelek WM, Vreijling J, Ruizendaal P, de Klein F, Marquart JA, Kuipers TB, Mei H, Zhang Y, Ahasan M, Johnson KK, Wang Y, Morgan BP, van Dijk M, Fluiter K, Andersen GR, Baas F. Gytz Olesen H, et al. Among authors: johnson kk. J Innate Immun. 2023;15(1):16-36. doi: 10.1159/000524587. Epub 2022 May 12. J Innate Immun. 2023. PMID: 35551129 Free PMC article.
The human complement receptor type 2 (CR2)/CR1 fusion protein TT32, a novel targeted inhibitor of the classical and alternative pathway C3 convertases, prevents arthritis in active immunization and passive transfer mouse models.
Fridkis-Hareli M, Storek M, Or E, Altman R, Katti S, Sun F, Peng T, Hunter J, Johnson K, Wang Y, Lundberg AS, Mehta G, Banda NK, Michael Holers V. Fridkis-Hareli M, et al. Mol Immunol. 2019 Jan;105:150-164. doi: 10.1016/j.molimm.2018.09.013. Epub 2018 Dec 1. Mol Immunol. 2019. PMID: 30513451 Free PMC article.
71 results