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Germline mutations in mitochondrial complex I reveal genetic and targetable vulnerability in IDH1-mutant acute myeloid leukaemia.
Bassal MA, Samaraweera SE, Lim K, Benard BA, Bailey S, Kaur S, Leo P, Toubia J, Thompson-Peach C, Nguyen T, Maung KZY, Casolari DA, Iarossi DG, Pagani IS, Powell J, Pitson S, Natera S, Roessner U, Lewis ID, Brown AL, Tenen DG, Robinson N, Ross DM, Majeti R, Gonda TJ, Thomas D, D'Andrea RJ. Bassal MA, et al. Nat Commun. 2022 May 12;13(1):2614. doi: 10.1038/s41467-022-30223-9. Nat Commun. 2022. PMID: 35551192 Free PMC article.
Rare variants in Fanconi anemia genes are enriched in acute myeloid leukemia.
Maung KZY, Leo PJ, Bassal M, Casolari DA, Gray JX, Bray SC, Pederson S, Singhal D, Samaraweera SE, Nguyen T, Cildir G, Marshall M, Ewing A, Duncan EL, Brown MA, Saal R, Tergaonkar V, To LB, Marlton P, Gill D, Lewis I, Deans AJ, Brown AL, D'Andrea RJ, Gonda TJ. Maung KZY, et al. Among authors: bassal m. Blood Cancer J. 2018 Jun 1;8(6):50. doi: 10.1038/s41408-018-0090-7. Blood Cancer J. 2018. PMID: 29891941 Free PMC article. No abstract available.
Identification of a targetable KRAS-mutant epithelial population in non-small cell lung cancer.
Maroni G, Bassal MA, Krishnan I, Fhu CW, Savova V, Zilionis R, Maymi VA, Pandell N, Csizmadia E, Zhang J, Storti B, Castaño J, Panella R, Li J, Gustafson CE, Fox S, Levy RD, Meyerovitz CV, Tramontozzi PJ, Vermilya K, De Rienzo A, Crucitta S, Bassères DS, Weetall M, Branstrom A, Giorgetti A, Ciampi R, Del Re M, Danesi R, Bizzarri R, Yang H, Kocher O, Klein AM, Welner RS, Bueno R, Magli MC, Clohessy JG, Ali A, Tenen DG, Levantini E. Maroni G, et al. Among authors: bassal ma. Commun Biol. 2021 Apr 14;4(1):370. doi: 10.1038/s42003-021-01897-6. Commun Biol. 2021. PMID: 33854168 Free PMC article.
Myeloid lncRNA LOUP mediates opposing regulatory effects of RUNX1 and RUNX1-ETO in t(8;21) AML.
Trinh BQ, Ummarino S, Zhang Y, Ebralidze AK, Bassal MA, Nguyen TM, Heller G, Coffey R, Tenen DE, van der Kouwe E, Fabiani E, Gurnari C, Wu CS, Angarica VE, Yang H, Chen S, Zhang H, Thurm AR, Marchi F, Levantini E, Staber PB, Zhang P, Voso MT, Pandolfi PP, Kobayashi SS, Chai L, Di Ruscio A, Tenen DG. Trinh BQ, et al. Among authors: bassal ma. Blood. 2021 Oct 14;138(15):1331-1344. doi: 10.1182/blood.2020007920. Blood. 2021. PMID: 33971010 Free PMC article.
Pseudogene-mediated DNA demethylation leads to oncogene activation.
Kwon J, Liu YV, Gao C, Bassal MA, Jones AI, Yang J, Chen Z, Li Y, Yang H, Chen L, Di Ruscio A, Tay Y, Chai L, Tenen DG. Kwon J, et al. Among authors: bassal ma. Sci Adv. 2021 Oct;7(40):eabg1695. doi: 10.1126/sciadv.abg1695. Epub 2021 Oct 1. Sci Adv. 2021. PMID: 34597139 Free PMC article.
Author Correction: Germline mutations in mitochondrial complex I reveal genetic and targetable vulnerability in IDH1-mutant acute myeloid leukaemia.
Bassal MA, Samaraweera SE, Lim K, Benard BA, Bailey S, Kaur S, Leo P, Toubia J, Thompson-Peach C, Nguyen T, Maung KZY, Casolari DA, Iarossi DG, Pagani IS, Powell J, Pitson S, Natera S, Roessner U, Lewis ID, Brown AL, Tenen DG, Robinson N, Ross DM, Majeti R, Gonda TJ, Thomas D, D'Andrea RJ. Bassal MA, et al. Nat Commun. 2022 Jul 15;13(1):4131. doi: 10.1038/s41467-022-31952-7. Nat Commun. 2022. PMID: 35840577 Free PMC article. No abstract available.
PU.1-c-Jun interaction is crucial for PU.1 function in myeloid development.
Zhao X, Bartholdy B, Yamamoto Y, Evans EK, Alberich-Jordà M, Staber PB, Benoukraf T, Zhang P, Zhang J, Trinh BQ, Crispino JD, Hoang T, Bassal MA, Tenen DG. Zhao X, et al. Among authors: bassal ma. Commun Biol. 2022 Sep 14;5(1):961. doi: 10.1038/s42003-022-03888-7. Commun Biol. 2022. PMID: 36104445 Free PMC article.
27 results