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Page 1
Central tolerance is impaired in the middle-aged thymic environment.
Lancaster JN, Keatinge-Clay DE, Srinivasan J, Li Y, Selden HJ, Nam S, Richie ER, Ehrlich LIR. Lancaster JN, et al. Among authors: selden hj. Aging Cell. 2022 Jun;21(6):e13624. doi: 10.1111/acel.13624. Epub 2022 May 13. Aging Cell. 2022. PMID: 35561351 Free PMC article.
Endogenous dendritic cells from the tumor microenvironment support T-ALL growth via IGF1R activation.
Triplett TA, Cardenas KT, Lancaster JN, Hu Z, Selden HJ, Jasso GJ, Balasubramanyam S, Chan K, Li L, Chen X, Marcogliese AN, Davé UP, Love PE, Ehrlich LI. Triplett TA, et al. Among authors: selden hj. Proc Natl Acad Sci U S A. 2016 Feb 23;113(8):E1016-25. doi: 10.1073/pnas.1520245113. Epub 2016 Feb 9. Proc Natl Acad Sci U S A. 2016. PMID: 26862168 Free PMC article.
Tumor-associated myeloid cells provide critical support for T-ALL.
Lyu A, Triplett TA, Nam SH, Hu Z, Arasappan D, Godfrey WH, Ames RY, Sarang A, Selden HJ, Lee CH, Georgiou G, Horton TM, Ehrlich LIR. Lyu A, et al. Among authors: selden hj. Blood. 2020 Oct 15;136(16):1837-1850. doi: 10.1182/blood.2020007145. Blood. 2020. PMID: 32845007 Free article.
The initial age-associated decline in early T-cell progenitors reflects fewer pre-thymic progenitors and altered signals in the bone marrow and thymus microenvironments.
Srinivasan J, Vasudev A, Shasha C, Selden HJ, Perez E Jr, LaFleur B, Sinari SA, Krueger A, Richie ER, Ehrlich LIR. Srinivasan J, et al. Among authors: selden hj. Aging Cell. 2023 Aug;22(8):e13870. doi: 10.1111/acel.13870. Epub 2023 May 23. Aging Cell. 2023. PMID: 37221658 Free PMC article.
Consensus tissue domain detection in spatial omics data using multiplex image labeling with regional morphology (MILWRM).
Kaur H, Heiser CN, McKinley ET, Ventura-Antunes L, Harris CR, Roland JT, Farrow MA, Selden HJ, Pingry EL, Moore JF, Ehrlich LIR, Shrubsole MJ, Spraggins JM, Coffey RJ, Lau KS, Vandekar SN. Kaur H, et al. Among authors: selden hj. Commun Biol. 2024 Oct 30;7(1):1295. doi: 10.1038/s42003-024-06281-8. Commun Biol. 2024. PMID: 39478141 Free PMC article.