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Page 1
Synthesis and In Vitro Characterization of Selective Cannabinoid CB2 Receptor Agonists: Biological Evaluation against Neuroblastoma Cancer Cells.
Gado F, Ferrisi R, Di Somma S, Napolitano F, Mohamed KA, Stevenson LA, Rapposelli S, Saccomanni G, Portella G, Pertwee RG, Laprairie RB, Malfitano AM, Manera C. Gado F, et al. Among authors: malfitano am. Molecules. 2022 May 7;27(9):3019. doi: 10.3390/molecules27093019. Molecules. 2022. PMID: 35566369 Free PMC article.
Anandamide inhibits adhesion and migration of breast cancer cells.
Grimaldi C, Pisanti S, Laezza C, Malfitano AM, Santoro A, Vitale M, Caruso MG, Notarnicola M, Iacuzzo I, Portella G, Di Marzo V, Bifulco M. Grimaldi C, et al. Among authors: malfitano am. Exp Cell Res. 2006 Feb 15;312(4):363-73. doi: 10.1016/j.yexcr.2005.10.024. Epub 2005 Dec 15. Exp Cell Res. 2006. PMID: 16343481
Rational design, synthesis and anti-proliferative properties of new CB2 selective cannabinoid receptor ligands: an investigation of the 1,8-naphthyridin-2(1H)-one scaffold.
Manera C, Saccomanni G, Malfitano AM, Bertini S, Castelli F, Laezza C, Ligresti A, Lucchesi V, Tuccinardi T, Rizzolio F, Bifulco M, Di Marzo V, Giordano A, Macchia M, Martinelli A. Manera C, et al. Among authors: malfitano am. Eur J Med Chem. 2012 Jun;52:284-94. doi: 10.1016/j.ejmech.2012.03.031. Epub 2012 Mar 24. Eur J Med Chem. 2012. PMID: 22483967
1,2-Dihydro-2-oxopyridine-3-carboxamides: the C-5 substituent is responsible for functionality switch at CB2 cannabinoid receptor.
Lucchesi V, Parkkari T, Savinainen JR, Malfitano AM, Allarà M, Bertini S, Castelli F, Del Carlo S, Laezza C, Ligresti A, Saccomanni G, Bifulco M, Di Marzo V, Macchia M, Manera C. Lucchesi V, et al. Among authors: malfitano am. Eur J Med Chem. 2014 Mar 3;74:524-32. doi: 10.1016/j.ejmech.2013.10.070. Epub 2014 Jan 21. Eur J Med Chem. 2014. PMID: 24518874
New quinolone- and 1,8-naphthyridine-3-carboxamides as selective CB2 receptor agonists with anticancer and immuno-modulatory activity.
Manera C, Malfitano AM, Parkkari T, Lucchesi V, Carpi S, Fogli S, Bertini S, Laezza C, Ligresti A, Saccomanni G, Savinainen JR, Ciaglia E, Pisanti S, Gazzerro P, Di Marzo V, Nieri P, Macchia M, Bifulco M. Manera C, et al. Among authors: malfitano am. Eur J Med Chem. 2015 Jun 5;97:10-8. doi: 10.1016/j.ejmech.2015.04.034. Epub 2015 Apr 24. Eur J Med Chem. 2015. PMID: 25935384
Structural insights into amyloid structures of the C-terminal region of nucleophosmin 1 in type A mutation of acute myeloid leukemia.
Di Natale C, La Manna S, Malfitano AM, Di Somma S, Florio D, Scognamiglio PL, Novellino E, Netti PA, Marasco D. Di Natale C, et al. Among authors: malfitano am. Biochim Biophys Acta Proteins Proteom. 2019 Jun;1867(6):637-644. doi: 10.1016/j.bbapap.2019.01.010. Epub 2019 Jan 30. Biochim Biophys Acta Proteins Proteom. 2019. PMID: 30710643
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