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Discovery of 2-Phenylquinolines with Broad-Spectrum Anti-coronavirus Activity.
Nizi MG, Persoons L, Corona A, Felicetti T, Cernicchi G, Massari S, Manfroni G, Vangeel L, Barreca ML, Esposito F, Jochmans D, Milia J, Cecchetti V, Schols D, Neyts J, Tramontano E, Sabatini S, De Jonghe S, Tabarrini O. Nizi MG, et al. Among authors: barreca ml. ACS Med Chem Lett. 2022 May 3;13(5):855-864. doi: 10.1021/acsmedchemlett.2c00123. eCollection 2022 May 12. ACS Med Chem Lett. 2022. PMID: 35571875 Free PMC article.
Re-evolution of the 2-phenylquinolines: ligand-based design, synthesis, and biological evaluation of a potent new class of Staphylococcus aureus NorA efflux pump inhibitors to combat antimicrobial resistance.
Sabatini S, Gosetto F, Iraci N, Barreca ML, Massari S, Sancineto L, Manfroni G, Tabarrini O, Dimovska M, Kaatz GW, Cecchetti V. Sabatini S, et al. Among authors: barreca ml. J Med Chem. 2013 Jun 27;56(12):4975-89. doi: 10.1021/jm400262a. Epub 2013 Jun 13. J Med Chem. 2013. PMID: 23710549
The versatile nature of the 6-aminoquinolone scaffold: identification of submicromolar hepatitis C virus NS5B inhibitors.
Manfroni G, Cannalire R, Barreca ML, Kaushik-Basu N, Leyssen P, Winquist J, Iraci N, Manvar D, Paeshuyse J, Guhamazumder R, Basu A, Sabatini S, Tabarrini O, Danielson UH, Neyts J, Cecchetti V. Manfroni G, et al. Among authors: barreca ml. J Med Chem. 2014 Mar 13;57(5):1952-63. doi: 10.1021/jm401362f. Epub 2013 Nov 6. J Med Chem. 2014. PMID: 24131104 Free PMC article.
Computer-aided design, synthesis and validation of 2-phenylquinazolinone fragments as CDK9 inhibitors with anti-HIV-1 Tat-mediated transcription activity.
Sancineto L, Iraci N, Massari S, Attanasio V, Corazza G, Barreca ML, Sabatini S, Manfroni G, Avanzi NR, Cecchetti V, Pannecouque C, Marcello A, Tabarrini O. Sancineto L, et al. Among authors: barreca ml. ChemMedChem. 2013 Dec;8(12):1941-53. doi: 10.1002/cmdc.201300287. Epub 2013 Oct 21. ChemMedChem. 2013. PMID: 24150998
105 results