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Altered CXCR4 dynamics at the cell membrane impairs directed cell migration in WHIM syndrome patients.
García-Cuesta EM, Rodríguez-Frade JM, Gardeta SR, D'Agostino G, Martínez P, Soler Palacios B, Cascio G, Wolf T, Mateos N, Ayala-Bueno R, Santiago CA, Lucas P, Llorente L, Allende LM, González-Granado LI, Martín-Cófreces N, Roda-Navarro P, Sallusto F, Sánchez-Madrid F, García-Parajo MF, Martínez-Muñoz L, Mellado M. García-Cuesta EM, et al. Among authors: martinez munoz l. Proc Natl Acad Sci U S A. 2022 May 24;119(21):e2119483119. doi: 10.1073/pnas.2119483119. Epub 2022 May 19. Proc Natl Acad Sci U S A. 2022. PMID: 35588454 Free PMC article.
CCR5/CD4/CXCR4 oligomerization prevents HIV-1 gp120IIIB binding to the cell surface.
Martínez-Muñoz L, Barroso R, Dyrhaug SY, Navarro G, Lucas P, Soriano SF, Vega B, Costas C, Muñoz-Fernández MÁ, Santiago C, Rodríguez Frade JM, Franco R, Mellado M. Martínez-Muñoz L, et al. Proc Natl Acad Sci U S A. 2014 May 13;111(19):E1960-9. doi: 10.1073/pnas.1322887111. Epub 2014 Apr 28. Proc Natl Acad Sci U S A. 2014. PMID: 24778234 Free PMC article.
Separating Actin-Dependent Chemokine Receptor Nanoclustering from Dimerization Indicates a Role for Clustering in CXCR4 Signaling and Function.
Martínez-Muñoz L, Rodríguez-Frade JM, Barroso R, Sorzano CÓS, Torreño-Pina JA, Santiago CA, Manzo C, Lucas P, García-Cuesta EM, Gutierrez E, Barrio L, Vargas J, Cascio G, Carrasco YR, Sánchez-Madrid F, García-Parajo MF, Mellado M. Martínez-Muñoz L, et al. Mol Cell. 2018 Apr 5;70(1):106-119.e10. doi: 10.1016/j.molcel.2018.02.034. Mol Cell. 2018. PMID: 29625032 Free article.
T Cell Migration in Rheumatoid Arthritis.
Mellado M, Martínez-Muñoz L, Cascio G, Lucas P, Pablos JL, Rodríguez-Frade JM. Mellado M, et al. Front Immunol. 2015 Jul 27;6:384. doi: 10.3389/fimmu.2015.00384. eCollection 2015. Front Immunol. 2015. PMID: 26284069 Free PMC article. Review.
Methods to immobilize GPCR on the surface of SPR sensors.
Martínez-Muñoz L, Barroso R, Paredes AG, Mellado M, Rodríguez-Frade JM. Martínez-Muñoz L, et al. Methods Mol Biol. 2015;1272:173-88. doi: 10.1007/978-1-4939-2336-6_12. Methods Mol Biol. 2015. PMID: 25563184
32 results