Chen X - Search Results

1

Understanding the contributions of VPS35 and the retromer in neurodegenerative disease.

Williams ET, Chen X, Otero PA, Moore DJ. Williams ET, et al. Among authors: chen x. Neurobiol Dis. 2022 Aug;170:105768. doi: 10.1016/j.nbd.2022.105768. Epub 2022 May 16. Neurobiol Dis. 2022. PMID: 35588987 Free PMC article. Review.

2

VPS35, the Retromer Complex and Parkinson's Disease.

Williams ET, Chen X, Moore DJ. Williams ET, et al. Among authors: chen x. J Parkinsons Dis. 2017;7(2):219-233. doi: 10.3233/JPD-161020. J Parkinsons Dis. 2017. PMID: 28222538 Free PMC article. Review.

3

Parkinson's disease-linked D620N VPS35 knockin mice manifest tau neuropathology and dopaminergic neurodegeneration.

Chen X, Kordich JK, Williams ET, Levine N, Cole-Strauss A, Marshall L, Labrie V, Ma J, Lipton JW, Moore DJ. Chen X, et al. Proc Natl Acad Sci U S A. 2019 Mar 19;116(12):5765-5774. doi: 10.1073/pnas.1814909116. Epub 2019 Mar 6. Proc Natl Acad Sci U S A. 2019. PMID: 30842285 Free PMC article.

4

Dopaminergic neurodegeneration induced by Parkinson's disease-linked G2019S LRRK2 is dependent on kinase and GTPase activity.

Nguyen APT, Tsika E, Kelly K, Levine N, Chen X, West AB, Boularand S, Barneoud P, Moore DJ. Nguyen APT, et al. Among authors: chen x. Proc Natl Acad Sci U S A. 2020 Jul 21;117(29):17296-17307. doi: 10.1073/pnas.1922184117. Epub 2020 Jul 6. Proc Natl Acad Sci U S A. 2020. PMID: 32631998 Free PMC article.

5

VPS35 and α-Synuclein fail to interact to modulate neurodegeneration in rodent models of Parkinson's disease.

Chen X, Tsika E, Levine N, Moore DJ. Chen X, et al. Mol Neurodegener. 2023 Aug 4;18(1):51. doi: 10.1186/s13024-023-00641-4. Mol Neurodegener. 2023. PMID: 37542299 Free PMC article.

6

Adult-onset deletion of ATP13A2 in mice induces progressive nigrostriatal pathway dopaminergic degeneration and lysosomal abnormalities.

Erb ML, Sipple K, Levine N, Chen X, Moore DJ. Erb ML, et al. Among authors: chen x. NPJ Parkinsons Dis. 2024 Jul 20;10(1):133. doi: 10.1038/s41531-024-00748-5. NPJ Parkinsons Dis. 2024. PMID: 39030200 Free PMC article.

7

Ethosuximide ameliorates neurodegenerative disease phenotypes by modulating DAF-16/FOXO target gene expression.

Chen X, McCue HV, Wong SQ, Kashyap SS, Kraemer BC, Barclay JW, Burgoyne RD, Morgan A. Chen X, et al. Mol Neurodegener. 2015 Sep 29;10:51. doi: 10.1186/s13024-015-0046-3. Mol Neurodegener. 2015. PMID: 26419537 Free PMC article.

8

Using C. elegans to discover therapeutic compounds for ageing-associated neurodegenerative diseases.

Chen X, Barclay JW, Burgoyne RD, Morgan A. Chen X, et al. Chem Cent J. 2015 Nov 26;9:65. doi: 10.1186/s13065-015-0143-y. eCollection 2015. Chem Cent J. 2015. PMID: 26617668 Free PMC article. Review.

9

Erratum to: Ethosuximide ameliorates neurodegenerative disease phenotypes by modulating DAF-16/FOXO target gene expression.

Chen X, McCue HV, Wong SQ, Kashyap SS, Kraemer BC, Barclay JW, Burgoyne RD, Morgan A. Chen X, et al. Mol Neurodegener. 2015 Oct 23;10:54. doi: 10.1186/s13024-015-0051-6. Mol Neurodegener. 2015. PMID: 26496836 Free PMC article.

10

Youthful Stem Cell Microenvironments: Rejuvenating Aged Bone Repair Through Mitochondrial Homeostasis Remodeling.

Zhou X, Tian X, Chen J, Li Y, Lv N, Liu H, Liu T, Yang H, Chen X, Xu Y, He F. Zhou X, et al. Among authors: chen x. Adv Sci (Weinh). 2025 Jan 17:e2409644. doi: 10.1002/advs.202409644. Online ahead of print. Adv Sci (Weinh). 2025. PMID: 39823536

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